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3CZJ
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BU of 3czj by Molmil
E. COLI (lacZ) BETA-GALACTOSIDASE (N460T) IN COMPLEX WITH D-GALCTOPYRANOSYL-1-ONE
Descriptor: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
Authors:Huber, R.E, Dugdale, M.L, Fraser, M.E, Tammam, S.D.
Deposit date:2008-04-29
Release date:2009-04-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Practical Considerations When Using Temperature to Obtain Rate Constants and Activation Thermodynamics of Enzymes with Two Catalytic Steps: Native and N460T-beta-Galactosidase (E. coli) as Examples.
Protein J., 28, 2009
5LDR
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BU of 5ldr by Molmil
Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain in complex with galactose
Descriptor: ACETATE ION, Beta-D-galactosidase, CHLORIDE ION, ...
Authors:Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G.
Deposit date:2016-06-27
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d.
Acta Crystallogr D Struct Biol, 72, 2016
8DHL
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BU of 8dhl by Molmil
Tannerella forsythia beta-glucuronidase (L2)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 2, ...
Authors:Lietzan, A.D, Redinbo, M.R.
Deposit date:2022-06-27
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Microbial beta-glucuronidases drive human periodontal disease etiology.
Sci Adv, 9, 2023
5A1A
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BU of 5a1a by Molmil
2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor
Descriptor: 2-phenylethyl 1-thio-beta-D-galactopyranoside, BETA-GALACTOSIDASE, MAGNESIUM ION, ...
Authors:Bartesaghi, A, Merk, A, Banerjee, S, Matthies, D, Wu, X, Milne, J, Subramaniam, S.
Deposit date:2015-04-29
Release date:2015-05-06
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
5EUV
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BU of 5euv by Molmil
Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Beta-D-galactosidase, ...
Authors:Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G.
Deposit date:2015-11-19
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d.
Acta Crystallogr D Struct Biol, 72, 2016
4V44
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BU of 4v44 by Molmil
E. COLI (lacZ) BETA-GALACTOSIDASE IN COMPLEX WITH 2-F-LACTOSE
Descriptor: 2-deoxy-2-fluoro-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Beta-Galactosidase, MAGNESIUM ION, ...
Authors:Juers, D.H, McCarter, J.D, Withers, S.G, Matthews, B.W.
Deposit date:2001-09-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase
Biochemistry, 40, 2001
7XYR
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BU of 7xyr by Molmil
Cystal Structure of Beta-glucuronidase from Bacteroides thetaiotaomicron
Descriptor: Beta-glucuronidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Teng, X, Wang, C.
Deposit date:2022-06-02
Release date:2023-07-05
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cystal Structure of Beta-glucuronidase from Bacteroides thetaiotaomicron
To Be Published
1YQ2
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BU of 1yq2 by Molmil
beta-galactosidase from Arthrobacter sp. C2-2 (isoenzyme C2-2-1)
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Skalova, T, Dohnalek, J, Spiwok, V, Lipovova, P, Vondrackova, E, Petrokova, H, Strnad, H, Kralova, B, Hasek, J.
Deposit date:2005-02-01
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cold-active beta-Galactosidase from Arthrobacter sp. C2-2 Forms Compact 660kDa Hexamers: Crystal Structure at 1.9A Resolution
J.Mol.Biol., 353, 2005
4TTG
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BU of 4ttg by Molmil
Beta-galactosidase (E. coli) in the presence of potassium chloride.
Descriptor: Beta-galactosidase, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Juers, D.H.
Deposit date:2014-06-20
Release date:2015-03-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Elucidating factors important for monovalent cation selectivity in enzymes: E. coli beta-galactosidase as a model.
Phys Chem Chem Phys, 17, 2015
4YPJ
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BU of 4ypj by Molmil
X-ray Structure of The Mutant of Glycoside Hydrolase
Descriptor: Beta galactosidase
Authors:Ishikawa, K, Kataoka, M, Yanamoto, T, Nakabayashi, M, Watanabe, M.
Deposit date:2015-03-13
Release date:2015-04-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of beta-galactosidase from Bacillus circulans ATCC 31382 (BgaD) and the construction of the thermophilic mutants.
Febs J., 282, 2015
8Q7Y
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BU of 8q7y by Molmil
ESIBD structure of beta-galactosidase
Descriptor: Beta-galactosidase
Authors:Esser, T, Boehning, J, Bharat, T.A.M, Rauschenbach, S.
Deposit date:2023-08-17
Release date:2024-01-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM of soft-landed beta-galactosidase: Gas-phase and native structures are remarkably similar.
Sci Adv, 10, 2024
8OHX
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BU of 8ohx by Molmil
Crystal structure of Beta-glucuronidase from Escherichia coli in complex with siastatin B derived inhibitor
Descriptor: (3~{S},4~{S},5~{S},6~{R})-4,5,6-tris(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase
Authors:Armstrong, Z, Yurong, C, Wu, L, Overkleeft, H.S, Davies, G.J.
Deposit date:2023-03-21
Release date:2024-01-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.
J.Am.Chem.Soc., 146, 2024
7NIT
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BU of 7nit by Molmil
X-ray structure of a multidomain BbgIII from Bifidobacterium bifidum
Descriptor: Beta-galactosidase, CALCIUM ION, GLYCEROL, ...
Authors:Moroz, O.V, Blagova, E, Lebedev, A.A, Sanchez Rodriguez, F, Rigden, D.J, Tams, J.W, Wilting, R, Vester, J.K, Longhin, E, Krogh, K.B.R, Pache, R.A, Davies, G.J, Wilson, K.S.
Deposit date:2021-02-14
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Multitasking in the gut: the X-ray structure of the multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions.
Acta Crystallogr D Struct Biol, 77, 2021
3LPF
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BU of 3lpf by Molmil
Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea
Descriptor: 1-[(6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea, Beta-glucuronidase
Authors:Wallace, B.D, Redinbo, M.R.
Deposit date:2010-02-05
Release date:2010-11-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.
Science, 330, 2010
3VD5
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BU of 3vd5 by Molmil
E. coli (lacZ) beta-galactosidase (N460S)
Descriptor: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD4
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BU of 3vd4 by Molmil
E. coli (lacZ) beta-galactosidase (N460D) in complex with IPTG
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3LPG
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BU of 3lpg by Molmil
Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)urea
Descriptor: 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-[(6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]urea, Beta-glucuronidase
Authors:Wallace, B.D, Redinbo, M.R.
Deposit date:2010-02-05
Release date:2010-11-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.425 Å)
Cite:Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.
Science, 330, 2010
1BHG
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BU of 1bhg by Molmil
HUMAN BETA-GLUCURONIDASE AT 2.6 A RESOLUTION
Descriptor: BETA-GLUCURONIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Jain, S, Drendel, W.B.
Deposit date:1996-03-04
Release date:1997-09-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structure of human beta-glucuronidase reveals candidate lysosomal targeting and active-site motifs.
Nat.Struct.Biol., 3, 1996
6X1Q
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BU of 6x1q by Molmil
1.8 Angstrom resolution structure of b-galactosidase with a 200 kV cryoARM electron microscope
Descriptor: Beta-galactosidase, MAGNESIUM ION, SODIUM ION
Authors:Merk, A, Fukumura, T, Zhu, X, Darling, J, Grisshammer, R, Ognjenovic, J, Subramaniam, S.
Deposit date:2020-05-19
Release date:2020-07-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (1.8 Å)
Cite:1.8 angstrom resolution structure of beta-galactosidase with a 200 kV CRYO ARM electron microscope.
Iucrj, 7, 2020
6H1P
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BU of 6h1p by Molmil
Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB - data collected at room temperature
Descriptor: Beta-galactosidase, SODIUM ION
Authors:Rutkiewicz, M, Bujacz, A, Bujacz, G.
Deposit date:2018-07-12
Release date:2019-06-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Structural features of cold-adapted dimeric GH2 beta-D-galactosidase from Arthrobacter sp. 32cB.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
6XXW
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BU of 6xxw by Molmil
Structure of beta-D-Glucuronidase for Dictyoglomus thermophilum.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucuronidase, ...
Authors:Lafite, P, Daniellou, R.
Deposit date:2020-01-28
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Thioglycoligation of aromatic thiols using a natural glucuronide donor.
Org.Biomol.Chem., 18, 2020
3BGA
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BU of 3bga by Molmil
Crystal structure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482
Descriptor: Beta-galactosidase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-11-26
Release date:2007-12-11
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure analysis of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482.
To be Published
6HPD
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BU of 6hpd by Molmil
The structure of a beta-glucuronidase from glycoside hydrolase family 2
Descriptor: BROMIDE ION, Beta-galactosidase (GH2), MAGNESIUM ION
Authors:Robb, C.S, Gerlach, N, Reisky, L, Bornshoeru, U, Hehemann, J.H.
Deposit date:2018-09-20
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan.
Nat.Chem.Biol., 15, 2019
1PX4
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BU of 1px4 by Molmil
E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E.
Deposit date:2003-07-02
Release date:2004-06-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase
Biochemistry, 42, 2003
1PX3
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BU of 1px3 by Molmil
E. COLI (LACZ) BETA-GALACTOSIDASE (G794A)
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, SODIUM ION, ...
Authors:Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E.
Deposit date:2003-07-02
Release date:2004-06-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase
Biochemistry, 42, 2003

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