1UZK
 
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only | | 分子名称: | CALCIUM ION, FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-13 | | 公開日 | 2006-05-24 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
|
|
7ALJ
 | | Structure of Drosophila Notch EGF domains 11-13 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ... | | 著者 | Suckling, R, Johnson, S, Lea, S.M. | | 登録日 | 2020-10-06 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
|
|
4D0E
 | | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-04-25 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
1UZP
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only. | | 分子名称: | FIBRILLIN-1, SAMARIUM (III) ION | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-15 | | 公開日 | 2004-04-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
|
|
2W86
 | | Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form | | 分子名称: | CALCIUM ION, FIBRILLIN-1, IODIDE ION | | 著者 | Jensen, S.A, Iqbal, S, Lowe, E.D, Redfield, C, Handford, P.A. | | 登録日 | 2009-01-09 | | 公開日 | 2009-05-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17, 2009
|
|
6POL
 | | Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, J, Pak, J.S, Ozkan, E. | | 登録日 | 2019-07-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
|
|
4CUD
 | | Human Notch1 EGF domains 11-13 mutant fucosylated at T466 | | 分子名称: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, alpha-L-fucopyranose | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-03-18 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5MWB
 | | Human Notch-2 EGF11-13 | | 分子名称: | CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ... | | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
|
|
2BOU
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium. | | 分子名称: | BARIUM ION, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-14 | | 公開日 | 2006-10-18 | | 最終更新日 | 2017-01-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
|
|
1H30
 | | C-terminal LG domain pair of human Gas6 | | 分子名称: | CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION | | 著者 | Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E. | | 登録日 | 2002-08-21 | | 公開日 | 2003-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
|
|
1UZJ
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | | 分子名称: | CALCIUM ION, FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-12 | | 公開日 | 2004-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
|
|
4CUF
 | | Human Notch1 EGF domains 11-13 mutant T466S | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-03-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4XL1
 | | Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Luca, V.C, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-01-13 | | 公開日 | 2015-03-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
|
|
1UZQ
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only. | | 分子名称: | FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-15 | | 公開日 | 2004-04-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
|
|
5FMA
 | | human Notch 1, EGF 4-7 | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | | 登録日 | 2015-11-02 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
|
|
1SZB
 | | Crystal structure of the human MBL-associated protein 19 (MAp19) | | 分子名称: | CALCIUM ION, mannose binding lectin-associated serine protease-2 related protein, MAp19 (19kDa) | | 著者 | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | | 登録日 | 2004-04-05 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin
J.Biol.Chem., 279, 2004
|
|
2BOX
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium. | | 分子名称: | CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ... | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-14 | | 公開日 | 2006-10-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
|
|
5UK5
 | |
5CIS
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-13 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
|
|
2VJ3
 | | Human Notch-1 EGFs 11-13 | | 分子名称: | CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ... | | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Lea, S.M. | | 登録日 | 2007-12-06 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
|
|
5CKN
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-15 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
|
|
2BO2
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium. | | 分子名称: | CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-07 | | 公開日 | 2006-08-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
|
|
1NT0
 | | Crystal structure of the CUB1-EGF-CUB2 region of MASP2 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Feinberg, H, Uitdehaag, J.C.M, Davies, J.M, Wallis, R, Drickamer, K, Weis, W.I. | | 登録日 | 2003-01-28 | | 公開日 | 2003-05-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Embo J., 22, 2003
|
|
5CKM
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-15 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
|
|
6POG
 | | Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wang, J, Pak, J.S, Ozkan, E. | | 登録日 | 2019-07-03 | | 公開日 | 2020-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | | 主引用文献 | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
|
|
