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5CIS

The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+

Summary for 5CIS
Entry DOI10.2210/pdb5cis/pdb
DescriptorMannan-binding lectin serine peptidase 2, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsmasp, cub1-egf-cub2, complement activation, lectin pathway, hydrolase
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains1
Total formula weight31868.42
Authors
Nan, R.,Furze, C.M.,Wright, D.W.,Gor, J.,Wallis, R.,Perkins, S.J. (deposition date: 2015-07-13, release date: 2017-01-18, Last modification date: 2024-01-10)
Primary citationNan, R.,Furze, C.M.,Wright, D.W.,Gor, J.,Wallis, R.,Perkins, S.J.
Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25:364-375, 2017
Cited by
PubMed: 28111019
DOI: 10.1016/j.str.2016.12.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.58 Å)
Structure validation

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