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2KL7
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Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
分子名称: Fibulin-4
著者Rossi, P, Chiang, Y, Anderson, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-30
公開日2009-07-21
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
To be Published
1Z6C
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BU of 1z6c by Molmil
Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S
分子名称: CALCIUM ION, Vitamin K-dependent protein S
著者Drakenberg, T, Ghasriani, H, Thulin, E, Thamlitz, A.M, Muranyi, A, Annila, A, Stenflo, J.
登録日2005-03-22
公開日2005-06-21
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3.
Biochemistry, 44, 2005
1LMJ
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BU of 1lmj by Molmil
NMR Study of the Fibrillin-1 cbEGF12-13 Pair of Ca2+ Binding Epidermal Growth Factor-like Domains
分子名称: CALCIUM ION, fibrillin 1
著者Smallridge, R.S, Whiteman, P, Werner, J.M, Campbell, I.D, Handford, P.A, Downing, A.K.
登録日2002-05-02
公開日2003-04-29
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution Structure and Dynamics of a Calcium Binding Epidermal Growth Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1.
J.Biol.Chem., 278, 2003
1EMN
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NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
分子名称: CALCIUM ION, FIBRILLIN
著者Downing, A.K, Campbell, I.D, Handford, P.A.
登録日1996-08-05
公開日1996-12-23
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1EMO
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BU of 1emo by Molmil
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES
分子名称: CALCIUM ION, FIBRILLIN
著者Downing, A.K, Campbell, I.D, Handford, P.A.
登録日1996-08-05
公開日1996-12-23
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
2BOX
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BU of 2box by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium.
分子名称: CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ...
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-14
公開日2006-10-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BO2
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BU of 2bo2 by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium.
分子名称: CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-07
公開日2006-08-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOU
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BU of 2bou by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium.
分子名称: BARIUM ION, CACODYLATE ION, CALCIUM ION, ...
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-14
公開日2006-10-18
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
5FM9
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BU of 5fm9 by Molmil
human Notch 1, EGF 4-7
分子名称: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
著者Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
登録日2015-11-02
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
1H30
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BU of 1h30 by Molmil
C-terminal LG domain pair of human Gas6
分子名称: CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION
著者Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E.
登録日2002-08-21
公開日2003-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
6POG
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BU of 6pog by Molmil
Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, J, Pak, J.S, Ozkan, E.
登録日2019-07-03
公開日2020-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
6POL
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BU of 6pol by Molmil
Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Wang, J, Pak, J.S, Ozkan, E.
登録日2019-07-04
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
5UK5
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BU of 5uk5 by Molmil
Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Garcia, K.C, Luca, V.C.
登録日2017-01-19
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.
Science, 355, 2017
6TQK
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BU of 6tqk by Molmil
Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ...
著者Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L.
登録日2019-12-16
公開日2020-11-04
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020
8UFB
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BU of 8ufb by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
1NT0
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BU of 1nt0 by Molmil
Crystal structure of the CUB1-EGF-CUB2 region of MASP2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Feinberg, H, Uitdehaag, J.C.M, Davies, J.M, Wallis, R, Drickamer, K, Weis, W.I.
登録日2003-01-28
公開日2003-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Embo J., 22, 2003
9ETN
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BU of 9etn by Molmil
Crystal structure of murine CRTAC1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Cartilage acidic protein 1, ...
著者Beugelink, J.W, Hof, H, Janssen, B.J.C.
登録日2024-03-26
公開日2024-07-31
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.584 Å)
主引用文献CRTAC1 has a Compact beta-propeller-TTR Core Stabilized by Potassium Ions.
J.Mol.Biol., 436, 2024
5B4X
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BU of 5b4x by Molmil
Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low density lipoprotein receptor-related protein 8, ...
著者Yasui, N, Hirai, H, Yamashita, K, Takagi, J, Nogi, T.
登録日2016-04-20
公開日2017-04-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.
To Be Published
7ALJ
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BU of 7alj by Molmil
Structure of Drosophila Notch EGF domains 11-13
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ...
著者Suckling, R, Johnson, S, Lea, S.M.
登録日2020-10-06
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7PFP
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BU of 7pfp by Molmil
Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
登録日2021-08-11
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7Q3N
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BU of 7q3n by Molmil
Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ...
著者Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
登録日2021-10-28
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
5MWB
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BU of 5mwb by Molmil
Human Notch-2 EGF11-13
分子名称: CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ...
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5MS9
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BU of 5ms9 by Molmil
Solution structure of Human Fibrillin-1 EGF2-EGF3-Hybrid1-cbEGF1 four domain fragment
分子名称: CALCIUM ION, Fibrillin-1
著者Robertson, I.B, Redfield, C, Handford, P.A.
登録日2017-01-01
公開日2017-08-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.
Structure, 25, 2017
8EM7
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BU of 8em7 by Molmil
Cryo-EM structure of LRP2 at pH 5.2
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
登録日2022-09-27
公開日2023-02-08
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
8EM4
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Cryo-EM structure of LRP2 at pH 7.5
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
登録日2022-09-26
公開日2023-02-08
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023

 

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