5FM9

human Notch 1, EGF 4-7

Summary for 5FM9

• Entry DOI: 10.2210/pdb5fm9/pdb
• Related: 5FMA
• Descriptor: NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION (3 entities in total)
• Functional Keywords: transcription, transmembrane, developmental, protein, notch signaling pathway, differentiation, phosphorylation, egf- like domain, regulation, receptor, activator, ank repeat, signalling, glycoprotein, extracellular, egf, notch, jagged, membrane
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cell membrane ; Single-pass type I membrane protein . Notch 1 intracellular domain: Nucleus : P46531
• Total number of polymer chains: 1
• Total formula weight: 16722.54

Authors

Weisshuhn, P.C.,Sheppard, D.,Taylor, P.,Whiteman, P.,Lea, S.M.,Handford, P.A.,Redfield, C. (deposition date: 2015-11-02, release date: 2016-04-20, Last modification date: 2024-01-10)

• Primary citation: Weisshuhn, P.C.,Sheppard, D.,Taylor, P.,Whiteman, P.,Lea, S.M.,Handford, P.A.,Redfield, C.; Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.; Structure, 24:555-, 2016; PubMed: 26996961; DOI: 10.1016/J.STR.2016.02.010

Experimental method

X-RAY DIFFRACTION (2.92 Å)