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2KXL
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Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state
分子名称: Cyclic nucleotide-gated potassium channel mll3241
著者Schunke, S, Stoldt, M, Willbold, D.
登録日2010-05-10
公開日2011-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
5T3N
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BU of 5t3n by Molmil
Sp-2Cl-cAMPS bound to PKAR CBD2
分子名称: (2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one, IODIDE ION, cAMP-dependent protein kinase regulatory subunit
著者Littler, D.R, Gilson, P.
登録日2016-08-26
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
J. Biol. Chem., 291, 2016
4D7T
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BU of 4d7t by Molmil
Structure of the SthK Carboxy-Terminal Region in complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, STHK_CNBD_CAMP
著者Kesters, D, Brams, M, Nys, M, Wijckmans, E, Spurny, R, Voets, T, Tytgat, J, Ulens, C.
登録日2014-11-27
公開日2015-02-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels.
Plos One, 10, 2015
4D7S
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Structure of the SthK Carboxy-Terminal Region in complex with cGMP
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, STHK_CNBD_CGMP
著者Kesters, D, Brams, M, Nys, M, Wijckmans, E, Spurny, R, Voets, T, Tytgat, J, Ulens, C.
登録日2014-11-27
公開日2015-02-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels.
Plos One, 10, 2015
6NP6
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BU of 6np6 by Molmil
Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis
分子名称: Crp/Fnr family transcriptional regulator, GLYCEROL
著者Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Scarsdale, J.N, Lewis, J.P.
登録日2019-01-17
公開日2019-06-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nitrosative Stress Sensing in Porphyromonas gingivalis: Structure and Mechanisms of the Heme Binding Transcriptional Regulator HcpR.
Acta Crystallogr D Struct Biol, 75, 2019
4Z07
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BU of 4z07 by Molmil
Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, ISOPROPYL ALCOHOL, SULFATE ION, ...
著者Kim, J.J, Reger, A.S, Arold, S.T, Kim, C.
登録日2015-03-25
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation.
Structure, 24, 2016
5BV6
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PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP
分子名称: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ...
著者Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W.
登録日2015-06-04
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J.Biol.Chem., 291, 2016
1CX4
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CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA
著者Diller, T.C, Xuong, N.H, Taylor, S.S.
登録日1999-08-28
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.
Structure, 9, 2001
2D93
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Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
分子名称: Rap guanine nucleotide exchange factor 6
著者Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-08
公開日2006-06-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
to be published
4QX5
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BU of 4qx5 by Molmil
Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: Insights for PKG agonist design
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, IODIDE ION, cGMP-dependent protein kinase 1
著者Huang, G.Y, Gerlits, O.O, Blakeley, M.P, Sankaran, B, Kovalevsky, A.Y, Kim, C.
登録日2014-07-18
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.318 Å)
主引用文献Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
Biochemistry, 53, 2014
4QXK
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Joint X-ray/neutron structure of PKGIbeta in complex with cGMP
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-dependent protein kinase 1
著者Kim, C, Gerlits, O, Kovalevsky, A, Huang, G.Y.
登録日2014-07-21
公開日2014-11-12
最終更新日2024-02-28
実験手法NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION
主引用文献Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
Biochemistry, 53, 2014
3MDP
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BU of 3mdp by Molmil
Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution
分子名称: 1,2-ETHANEDIOL, Cyclic nucleotide-binding domain (CNMP-BD) protein, SUCCINIC ACID
著者Joint Center for Structural Genomics (JCSG)
登録日2010-03-30
公開日2010-05-19
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution
To be published
5H5O
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BU of 5h5o by Molmil
A cyclic-GMP-dependent signalling pathway regulates bacterial phytopathogenesis
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Diguanylate cyclase
著者Chin, K.H, Chou, S.-H.
登録日2016-11-08
公開日2017-05-24
実験手法X-RAY DIFFRACTION (2.122 Å)
主引用文献A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis
EMBO J., 32, 2013
6SYG
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BU of 6syg by Molmil
Crystal structure of the Cyclic Nucleotide-Binding Homology Domain of the human KCNH2 channel
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Ben-Bassat, A, Giladi, M, Haitin, Y.
登録日2019-09-27
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge.
J.Gen.Physiol., 152, 2020
5J3U
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BU of 5j3u by Molmil
Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Protein Kinase A
著者El Bakkouri, M, Walker, J.R, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, L, Structural Genomics Consortium (SGC)
登録日2016-03-31
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP
To Be Published
5J48
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PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP
分子名称: 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ...
著者Campbell, J.C, Sankaran, B, Kim, C.W.
登録日2016-03-31
公開日2017-04-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
1RL3
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BU of 1rl3 by Molmil
Crystal structure of cAMP-free R1a subunit of PKA
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Brown, S, Xuong, N.-H, Taylor, S.S.
登録日2003-11-24
公開日2004-07-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.
Structure, 12, 2004
1U12
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BU of 1u12 by Molmil
M. loti cyclic nucleotide binding domain mutant
分子名称: IODIDE ION, POTASSIUM ION, SULFATE ION, ...
著者Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
登録日2004-07-14
公開日2004-11-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel
Cell(Cambridge,Mass.), 119, 2004
1RGS
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BU of 1rgs by Molmil
REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP DEPENDENT PROTEIN KINASE
著者Su, Y, Dostmann, W.R.G, Herberg, F.W, Durick, K, Xuong, N.-H, Ten Eyck, L, Taylor, S.S, Varughese, K.I.
登録日1995-06-21
公開日1996-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains.
Science, 269, 1995
1VP6
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M.loti ion channel cylic nucleotide binding domain
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel
著者Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
登録日2004-10-14
公開日2004-10-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
Cell(Cambridge,Mass.), 119, 2004
4F8A
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BU of 4f8a by Molmil
Cyclic nucleotide binding-homology domain from mouse EAG1 potassium channel
分子名称: Potassium voltage-gated channel subfamily H member 1
著者Marques-Carvalho, M.J, Sahoo, N, Muskett, F.W, Vieira-Pires, R.S, Gabant, G, Cadene, M, Schonherr, R, Morais-Cabral, J.H.
登録日2012-05-17
公開日2012-07-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.
J.Mol.Biol., 423, 2012
4HBN
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BU of 4hbn by Molmil
Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L.
登録日2012-09-28
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
2K0G
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BU of 2k0g by Molmil
Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein
著者Schunke, S, Stoldt, M, Willbold, D.
登録日2008-02-02
公開日2009-02-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP.
Embo Rep., 10, 2009
2Z69
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Crystal Structure of the sensor domain of the transcriptional regulator DNR from Pseudomonas aeruginosa
分子名称: DNR protein
著者Giardina, G, Johnson, K.A, Di Matteo, A.
登録日2007-07-24
公開日2008-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR.
J.Mol.Biol., 378, 2008
2MHF
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BU of 2mhf by Molmil
Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
分子名称: Uncharacterized protein
著者Li, Q, Ng, H.
登録日2013-11-21
公開日2014-04-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel.
J.Struct.Biol., 186, 2014

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