6O03

Monobody (MC17) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001784	molecular_function	phosphotyrosine residue binding
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005509	molecular_function	calcium ion binding
A	0007166	biological_process	cell surface receptor signaling pathway
A	0023051	biological_process	regulation of signaling
B	0001784	molecular_function	phosphotyrosine residue binding
B	0004842	molecular_function	ubiquitin-protein transferase activity
B	0005509	molecular_function	calcium ion binding
B	0007166	biological_process	cell surface receptor signaling pathway
B	0023051	biological_process	regulation of signaling

Functional Information from PROSITE/UniProt

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGNSP

Chain	Residue	Details
C	GLY39-PRO46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0007744|PDB:1B47, ECO:0007744|PDB:2CBL

Chain	Residue	Details
B	ASP229
A	GLU240
B	THR231
B	ASN233
B	TYR235
B	GLU240
A	ASP229
A	THR231
A	ASN233
A	TYR235

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	ARG294
A	ARG294

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