6O03

Monobody (MC17) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL

Summary for 6O03

• Entry DOI: 10.2210/pdb6o03/pdb
• Descriptor: E3 ubiquitin-protein ligase CBL, Monobody (MC17) (2 entities in total)
• Functional Keywords: monobody, sh2 domain, e3 ligase, inhibitor, synthetic binder, protein binding, transferase-protein binding, inhibitor complex, transferase/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 91455.06

Authors

Kukenshoner, T.,Pojer, F.,Hantschel, O. (deposition date: 2019-02-15, release date: 2020-08-19, Last modification date: 2024-03-13)

• Primary citation: Kukenshoner, T.,Pojer, F.,Hantschel, O.; Monobody (MC17) bound to tyrosine kinase binding domain of E3 ligase CBL; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.3 Å)