5XQ0

Structural basis of kindlin-mediated integrin recognition and activation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005856	cellular_component	cytoskeleton
A	0007229	biological_process	integrin-mediated signaling pathway
B	0005856	cellular_component	cytoskeleton
B	0007229	biological_process	integrin-mediated signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue GOL A 801

Chain	Residue
A	TRP562
A	GLU567
A	GLY569
A	ILE570

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	PHE609
B	PHE609

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
A	SER209
B	SER209

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q96AC1

Chain	Residue	Details
A	PHE577
B	GLU231
B	LEU565
B	PHE577
A	GLU231
A	LEU565

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P05556

Chain	Residue	Details
A	SER785
B	SER785

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P05556

Chain	Residue	Details
B	THR789
A	THR789

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P05556

Chain	Residue	Details
A	LYS794
B	LYS794

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0000250|UniProtKB:P05556

Chain	Residue	Details
A	LYS794
B	LYS794

---