4I7H

Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	1900376	biological_process	regulation of secondary metabolite biosynthetic process
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding
B	1900376	biological_process	regulation of secondary metabolite biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI A 201

Chain	Residue
A	HIS4
A	HIS6
A	ASN15
A	HIS19
A	HIS97
A	HIS99

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 202

Chain	Residue
A	CYS147
A	CYS104
A	CYS107
A	CYS144

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 201

Chain	Residue
B	CYS104
B	CYS107
B	CYS144
B	CYS147

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI B 202

Chain	Residue
B	HIS4
B	HIS6
B	ASN15
B	HIS19
B	HIS97
B	HIS99

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