4C16
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CkCdpGfsGLkC |
| Chain | Residue | Details |
| A | CYS142-CYS153 |
| site_id | PS00615 |
| Number of Residues | 28 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CVeiyikrekdvgmWNDERCskkkl.ALC |
| Chain | Residue | Details |
| A | CYS90-CYS117 |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CkCdpGFsglk....C |
| Chain | Residue | Details |
| A | CYS142-CYS153 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:1ESL, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY |
| Chain | Residue | Details |
| A | GLU80 | |
| B | GLU80 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11081633, ECO:0000269|PubMed:26117840, ECO:0007744|PDB:1ESL, ECO:0007744|PDB:1G1T, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY |
| Chain | Residue | Details |
| A | ASN82 | |
| A | ASN105 | |
| A | ASP106 | |
| B | ASN82 | |
| B | ASN105 | |
| B | ASP106 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11081633, ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY |
| Chain | Residue | Details |
| A | GLU88 | |
| B | GLU88 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY |
| Chain | Residue | Details |
| A | GLU92 | |
| B | GLU92 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY |
| Chain | Residue | Details |
| A | ASN4 | |
| B | ASN139 | |
| B | ASN158 | |
| B | ASN178 | |
| B | ASN182 | |
| B | ASN244 | |
| A | ASN124 | |
| A | ASN139 | |
| A | ASN158 | |
| A | ASN178 | |
| A | ASN182 | |
| A | ASN244 | |
| B | ASN4 | |
| B | ASN124 |
