3SQO

PCSK9 J16 Fab complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR198-HIS204

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Cleavage; by autolysis => ECO:0000269|PubMed:14622975

Chain	Residue	Details
P	GLN152
A	HIS226
A	SER386

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Sulfotyrosine => ECO:0000269|PubMed:16912035

Chain	Residue	Details
P	TYR38

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by FAM20C => ECO:0000269|PubMed:18498363, ECO:0000269|PubMed:26091039

Chain	Residue	Details
P	SER47

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16912035

Chain	Residue	Details
A	ASN533

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