3RNU
Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0035458 | biological_process | cellular response to interferon-beta |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0035458 | biological_process | cellular response to interferon-beta |
| C | 0002218 | biological_process | activation of innate immune response |
| C | 0035458 | biological_process | cellular response to interferon-beta |
| D | 0002218 | biological_process | activation of innate immune response |
| D | 0035458 | biological_process | cellular response to interferon-beta |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 6 |
| Chain | Residue |
| A | ARG721 |
| A | HIS757 |
| A | ILE758 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 2 |
| Chain | Residue |
| B | PRO646 |
| B | THR648 |
| B | LEU649 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 4 |
| Chain | Residue |
| B | ILE758 |
| B | ARG721 |
| B | LEU722 |
| B | HIS757 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT C 3 |
| Chain | Residue |
| C | ARG721 |
| C | LEU722 |
| C | HIS757 |
| C | ILE758 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 1 |
| Chain | Residue |
| D | HOH34 |
| D | PRO646 |
| D | THR648 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT D 5 |
| Chain | Residue |
| D | PHE589 |
| D | ARG721 |
| D | LEU722 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT D 7 |
| Chain | Residue |
| D | ARG638 |
| D | ASN639 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | SER575 | |
| B | SER575 | |
| C | SER575 | |
| D | SER575 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:22691496 |
| Chain | Residue | Details |
| A | LYS598 | |
| A | LYS614 | |
| B | LYS598 | |
| B | LYS614 | |
| C | LYS598 | |
| C | LYS614 | |
| D | LYS598 | |
| D | LYS614 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS683 | |
| B | LYS683 | |
| C | LYS683 | |
| D | LYS683 |
