1C7S

BETA-N-ACETYLHEXOSAMINIDASE MUTANT D539A COMPLEXED WITH DI-N-ACETYL-BETA-D-GLUCOSAMINE (CHITOBIASE)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004563	molecular_function	beta-N-acetylhexosaminidase activity
A	0005764	cellular_component	lysosome
A	0005975	biological_process	carbohydrate metabolic process
A	0006032	biological_process	chitin catabolic process
A	0006689	biological_process	ganglioside catabolic process
A	0016020	cellular_component	membrane
A	0016231	molecular_function	beta-N-acetylglucosaminidase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030203	biological_process	glycosaminoglycan metabolic process
A	0030246	molecular_function	carbohydrate binding
A	0030247	molecular_function	polysaccharide binding
A	0042597	cellular_component	periplasmic space
A	0102148	molecular_function	N-acetyl-beta-D-galactosaminidase activity

Functional Information from PROSITE/UniProt

site_id	PS00041
Number of Residues	46
Details	HTH_ARAC_FAMILY_1 Bacterial regulatory proteins, araC family signature. KLepTAkfSgfpagkaveIpVVAEYwQLfrndfLprwYATsgDaKP

Chain	Residue	Details
A	LYS114-PRO159

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	GLU540

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1qba

Chain	Residue	Details
A	GLU540
A	ALA539

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site_id	MCSA1
Number of Residues	2
Details	M-CSA 899

Chain	Residue	Details
A	ALA539	electrostatic stabiliser, modifies pKa, steric role
A	GLU540	proton shuttle (general acid/base)

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