1C7S

BETA-N-ACETYLHEXOSAMINIDASE MUTANT D539A COMPLEXED WITH DI-N-ACETYL-BETA-D-GLUCOSAMINE (CHITOBIASE)

Summary for 1C7S

Entry DOI	10.2210/pdb1c7s/pdb
Related	1C7T 1QBA 1QBB 1QBC
Descriptor	BETA-N-ACETYLHEXOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total)
Functional Keywords	glycosyl hydrolase, beta-n-acetylhexosaminidase, chitinolysis, a/b(tim)-barrel, site directed mutagenesis, substrate nucleophile stabilizer mutation, hydrolase
Biological source	Serratia marcescens
Cellular location	Periplasm: Q54468
Total number of polymer chains	1
Total formula weight	96749.58
Authors	Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B. (deposition date: 2000-03-14, release date: 2000-09-20, Last modification date: 2023-08-09)
Primary citation	Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B. Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540. J.Mol.Biol., 300:611-617, 2000 Cited by PubMed: 10884356 DOI: 10.1006/jmbi.2000.3906 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation