Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3H3G
DownloadVisualize
BU of 3h3g by Molmil
Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP)
Descriptor: Fusion protein of Maltose-binding periplasmic domain and human parathyroid hormone receptor extracellular domain, Parathyroid hormone-related protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2009-04-16
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.
J.Biol.Chem., 284, 2009
3L2J
DownloadVisualize
BU of 3l2j by Molmil
Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)
Descriptor: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2009-12-15
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation.
J.Biol.Chem., 285, 2010
2CXK
DownloadVisualize
BU of 2cxk by Molmil
Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1)
Descriptor: SULFATE ION, calmodulin binding transcription activator 1
Authors:Pioszak, A.A, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-30
Release date:2005-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1)
To be Published
2CWW
DownloadVisualize
BU of 2cww by Molmil
Crystal structure of Thermus thermophilus TTHA1280, a putative SAM-dependent RNA methyltransferase, in complex with S-adenosyl-L-homocysteine
Descriptor: ACETIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-27
Release date:2005-10-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
2CWZ
DownloadVisualize
BU of 2cwz by Molmil
Crystal structure of the Thermus thermophilus hypothetical protein TTHA0967, a thioesterase superfamily member
Descriptor: 1,2-ETHANEDIOL, thioesterase family protein
Authors:Pioszak, A.A, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-27
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the Thermus thermophilus hypothetical protein TTHA0967, a thioesterase superfamily member
To be Published
1WN9
DownloadVisualize
BU of 1wn9 by Molmil
Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
Descriptor: ACETIC ACID, the hypothetical protein (TT1805)
Authors:Pioszak, A.A, Kishishita, S, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-07-28
Release date:2005-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
To be Published
1WXX
DownloadVisualize
BU of 1wxx by Molmil
Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
Descriptor: PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-02
Release date:2005-08-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
1WNA
DownloadVisualize
BU of 1wna by Molmil
Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
Descriptor: the hypothetical protein (TT1805)
Authors:Pioszak, A.A, Kishishita, S, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-07-28
Release date:2005-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
To be Published
1WXW
DownloadVisualize
BU of 1wxw by Molmil
Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
Descriptor: HEXANE-1,6-DIOL, hypothetical protein TTHA1280
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-02
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
3C4M
DownloadVisualize
BU of 3c4m by Molmil
Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)
Descriptor: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2008-01-30
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular recognition of parathyroid hormone by its G protein-coupled receptor.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EHU
DownloadVisualize
BU of 3ehu by Molmil
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Corticoliberin, ...
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2008-09-14
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
3EHT
DownloadVisualize
BU of 3eht by Molmil
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
Descriptor: Corticoliberin, FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2008-09-14
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
3EHS
DownloadVisualize
BU of 3ehs by Molmil
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, fusion protein of CRFR1 extracellular domain and MBP
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2008-09-14
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
6V2E
DownloadVisualize
BU of 6v2e by Molmil
Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant
Descriptor: ADM, AMINO GROUP, FORMIC ACID, ...
Authors:Booe, J.M, Pioszak, A.A.
Deposit date:2019-11-22
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors.
Acs Pharmacol Transl Sci, 3, 2020
1R62
DownloadVisualize
BU of 1r62 by Molmil
Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
Descriptor: Nitrogen regulation protein NR(II)
Authors:Song, Y, Peisach, D, Pioszak, A.A, Xu, Z, Ninfa, A.J.
Deposit date:2003-10-14
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
6PGQ
DownloadVisualize
BU of 6pgq by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Calcitonin, ...
Authors:Lee, S, Pioszak, A.A.
Deposit date:2019-06-24
Release date:2020-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
6PFO
DownloadVisualize
BU of 6pfo by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin, Maltodextrin-binding protein,Calcitonin receptor, ...
Authors:Lee, S, Pioszak, A.A.
Deposit date:2019-06-21
Release date:2020-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
3N96
DownloadVisualize
BU of 3n96 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
Descriptor: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
Deposit date:2010-05-28
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N93
DownloadVisualize
BU of 3n93 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3
Descriptor: GLYCEROL, Maltose binding protein-CRFR2 alpha, Urocortin-3, ...
Authors:Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
Deposit date:2010-05-28
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N95
DownloadVisualize
BU of 3n95 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
Descriptor: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
Deposit date:2010-05-28
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
6D1U
DownloadVisualize
BU of 6d1u by Molmil
Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin
Descriptor: ADM2, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, SODIUM ION, ...
Authors:Pioszak, A, Roehrkasse, A.
Deposit date:2018-04-12
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analyses reveal a triple beta-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design.
J. Biol. Chem., 293, 2018
4RWF
DownloadVisualize
BU of 4rwf by Molmil
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Descriptor: 1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
4RWG
DownloadVisualize
BU of 4rwg by Molmil
Crystal structure of the CLR:RAMP1 extracellular domain heterodimer with bound high affinity CGRP analog
Descriptor: CGRP analog, MAGNESIUM ION, Maltose-binding periplasmic protein, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
5V6Y
DownloadVisualize
BU of 5v6y by Molmil
Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
Descriptor: ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A, Booe, J.
Deposit date:2017-03-17
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
3N94
DownloadVisualize
BU of 3n94 by Molmil
Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain
Descriptor: Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Kumar, S, Pioszak, A.A, Swaminathan, K, Xu, H.E.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors.
Plos One, 6, 2011

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon