Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2Y2G
DownloadVisualize
BU of 2y2g by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (A01)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2N
DownloadVisualize
BU of 2y2n by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E07)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2Q
DownloadVisualize
BU of 2y2q by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (Z06)
Descriptor: (3-acetamido-5-carboxy-phenyl)-trihydroxy-boron, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2WK0
DownloadVisualize
BU of 2wk0 by Molmil
Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate.
Descriptor: (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, BETA-LACTAMASE, CHLORIDE ION, ...
Authors:Sauvage, E, Zervosen, A, Dive, G, Herman, R, Kerff, F, Amoroso, A, Fonze, E, Pratt, R.F, Luxen, A, Charlier, P.
Deposit date:2009-06-03
Release date:2009-12-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
2P7C
DownloadVisualize
BU of 2p7c by Molmil
Solution structure of the bacillus licheniformis BlaI monomeric form in complex with the blaP half-operator.
Descriptor: Penicillinase repressor, Strand 1 of Twelve base-pair DNA, Strand 2 of Twelve base-pair DNA
Authors:Boudet, J, Duval, V, Van Melckebeke, H, Blackledge, M, Amoroso, A, Joris, B, Simorre, J.-P.
Deposit date:2007-03-20
Release date:2007-06-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against beta-lactam antibiotics.
Nucleic Acids Res., 35, 2007
2Y2M
DownloadVisualize
BU of 2y2m by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E08)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2H
DownloadVisualize
BU of 2y2h by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA2)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2J
DownloadVisualize
BU of 2y2j by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA4)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol, 6, 2011
2Y2O
DownloadVisualize
BU of 2y2o by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (EO9)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2I
DownloadVisualize
BU of 2y2i by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA3)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2K
DownloadVisualize
BU of 2y2k by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA5)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol, 6, 2011
2Y2P
DownloadVisualize
BU of 2y2p by Molmil
Penicillin-binding protein 1b (pbp-1b) in complex with an alkyl boronate (z10)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2L
DownloadVisualize
BU of 2y2l by Molmil
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E06)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SODIUM ION, ...
Authors:Contreras-Martel, C, Amoroso, A, Woon, E.C, Zervosen, A, Inglis, S, Martins, A, Verlaine, O, Rydzik, A, Job, V, Luxen, A, Joris, B, Schofield, C.J, Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2XPC
DownloadVisualize
BU of 2xpc by Molmil
Second-generation sulfonamide inhibitors of MurD: Activity optimisation with conformationally rigid analogues of D-glutamic acid
Descriptor: (1R,3R,4S)-4-[({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)AMINO]CYCLOHEXANE-1,3-DICARBOXYLIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Sosic, I, Barreteau, H, Simcic, M, Sink, R, Cesar, J, Golic-Grdadolnik, S, Contreras-Martel, C, Dessen, A, Amoroso, A, Joris, B, Blanot, D, Gobec, S.
Deposit date:2010-08-26
Release date:2011-05-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Second-Generation Sulfonamide Inhibitors of D- Glutamic Acid-Adding Enzyme: Activity Optimisation with Conformationally Rigid Analogues of D- Glutamic Acid.
Eur.J.Med.Chem, 46, 2011
3D30
DownloadVisualize
BU of 3d30 by Molmil
Structure of an expansin like protein from Bacillus Subtilis at 1.9A resolution
Descriptor: Expansin like protein, FORMIC ACID, GLYCEROL
Authors:Kerff, F, Petrella, S, Herman, R, Sauvage, E, Joris, B, Charlier, P.
Deposit date:2008-05-09
Release date:2008-10-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization.
Proc.Natl.Acad.Sci.USA, 105, 2008
2BH0
DownloadVisualize
BU of 2bh0 by Molmil
Crystal structure of a SeMet derivative of EXPA from Bacillus subtilis at 2.5 angstrom
Descriptor: YOAJ
Authors:Petrella, S, Herman, R, Sauvage, E, Filee, P, Joris, B, Charlier, P.
Deposit date:2005-01-06
Release date:2006-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure and Activity of Bacillus Subtilis Yoaj (Exlx1), a Bacterial Expansin that Promotes Root Colonization.
Proc.Natl.Acad.Sci.USA, 105, 2008
2WKE
DownloadVisualize
BU of 2wke by Molmil
Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate.
Descriptor: (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ...
Authors:Sauvage, E, Herman, R, Kerff, F, Charlier, P.
Deposit date:2009-06-10
Release date:2009-12-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
4WRN
DownloadVisualize
BU of 4wrn by Molmil
Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Uromodulin, ZINC ION, ...
Authors:Bokhove, M, De Sanctis, D, Jovine, L.
Deposit date:2014-10-24
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A structured interdomain linker directs self-polymerization of human uromodulin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4NYT
DownloadVisualize
BU of 4nyt by Molmil
L-Ficolin Complexed to Phosphocholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Laffly, E, Gaboriaud, C, Martin, L, Thielens, N.
Deposit date:2013-12-11
Release date:2014-10-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic Acid
J.Immunol., 193, 2014
4IQT
DownloadVisualize
BU of 4iqt by Molmil
Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
Descriptor: 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase
Authors:Gouge, J, Delarue, M.
Deposit date:2013-01-13
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQU
DownloadVisualize
BU of 4iqu by Molmil
Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
Descriptor: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, SODIUM ION
Authors:Gouge, J, Delarue, M.
Deposit date:2013-01-13
Release date:2013-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQV
DownloadVisualize
BU of 4iqv by Molmil
Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA
Descriptor: 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2013-01-13
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQW
DownloadVisualize
BU of 4iqw by Molmil
Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA
Descriptor: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, 5'-D(*GP*CP*CP*G)-3', DNA nucleotidylexotransferase, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2013-01-13
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
6G88
DownloadVisualize
BU of 6g88 by Molmil
Crystal structure of Enterococcus Faecium D63r Penicillin-Binding protein 5 (PBP5fm)
Descriptor: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyrrolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Low affinity penicillin-binding protein 5 (PBP5), SULFATE ION
Authors:Sauvage, E, El Gachi, M, Herman, R, Kerff, F, Charlier, P.
Deposit date:2018-04-08
Release date:2019-04-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of inactivation of Enterococcus faecium penicillin binding protein 5 by ceftobiprole.
To Be Published
6TQK
DownloadVisualize
BU of 6tqk by Molmil
Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ...
Authors:Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L.
Deposit date:2019-12-16
Release date:2020-11-04
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020

 

12>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon