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6KQV
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BU of 6kqv by Molmil
Solution Structure of the UbL Domain of USP19
分子名称: Ubiquitin carboxyl-terminal hydrolase 19
著者Xue, W, Hu, H.Y.
登録日2019-08-19
公開日2020-08-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
2JAX
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BU of 2jax by Molmil
Universal Stress Protein Rv2623 from Mycobaterium Tuberculosis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, HYPOTHETICAL PROTEIN TB31.7, UNKNOWN ATOM OR ION
著者Oberschall, A, Bourenkov, G, Strizhov, N, Bartunik, H.D.
登録日2006-11-30
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Crystal Structure of Universal Stress Protein Rv2623 from Mycobacterium Tuberculosis
To be Published
7SMI
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BU of 7smi by Molmil
Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea
分子名称: L-galactose dehydrogenase
著者Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C.
登録日2021-10-26
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis.
Plant Cell.Physiol., 63, 2022
7SML
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BU of 7sml by Molmil
Crystal Structure of L-GALACTONO-1,4-LACTONE DEHYDROGENASE de Myrciaria dubia
分子名称: L-GALACTONO-1,4-LACTONE DEHYDROGENASE
著者Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C.
登録日2021-10-26
公開日2022-11-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the Smirnoff-Wheeler pathway for vitamin C production in the Amazon fruit Camu-Camu.
J.Exp.Bot., 2024
2DAG
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BU of 2dag by Molmil
Solution Structure of the First UBA Domain in the Human Ubiquitin Specific Protease 5 (Isopeptidase 5)
分子名称: Ubiquitin carboxyl-terminal hydrolase 5
著者Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2006-06-14
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution Structure of the First UBA Domain in the Human Ubiquitin Specific Protease 5 (Isopeptidase 5)
To be Published
2DAK
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BU of 2dak by Molmil
Solution Structure of the Second UBA Domain in the Human Ubiquitin Specific Protease 5 (Isopeptidase 5)
分子名称: Ubiquitin carboxyl-terminal hydrolase 5
著者Zhao, C, Kigawa, T, Sato, M, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2006-06-14
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution Structure of the Second UBA Domain in the Human Ubiquitin Specific Protease 5 (Isopeptidase 5)
To be Published
7SVQ
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BU of 7svq by Molmil
Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea in complex with NAD+
分子名称: L-galactose dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C.
登録日2021-11-19
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis.
Plant Cell.Physiol., 63, 2022
7CJM
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BU of 7cjm by Molmil
SARS CoV-2 PLpro in complex with GRL0617
分子名称: 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION
著者Fu, Z, Huang, H.
登録日2020-07-11
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery.
Nat Commun, 12, 2021
2MUX
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BU of 2mux by Molmil
SUMO2 non-covalently interacts with USP25 and downregulates its activity
分子名称: Ubiquitin carboxyl-terminal hydrolase 25
著者Shi, L, Zhang, N, Wen, Y.
登録日2014-09-18
公開日2016-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献SUMO2 non-covalently interacts with USP25 and downregulates its activity
To be Published
3ZLZ
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BU of 3zlz by Molmil
Lys6-linked tri-ubiquitin
分子名称: UBIQUITIN, ZINC ION
著者Hospenthal, M.K, Freund, S.M.V, Komander, D.
登録日2013-02-04
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Assembly, Analysis and Architecture of Atypical Ubiquitin Chains
Nat.Struct.Mol.Biol., 20, 2013
4A3O
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BU of 4a3o by Molmil
Crystal structure of the USP15 DUSP-UBL monomer
分子名称: GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
4A3P
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BU of 4a3p by Molmil
Structure of USP15 DUSP-UBL deletion mutant
分子名称: ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
5V5T
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BU of 5v5t by Molmil
Crystal structure of leucine-rich protein regulator, ElrR, from Enterococcus faecalis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Conserved domain protein
著者De Groote, M.C.R, Camargo, I.L, Serror, P, Horjales, E.
登録日2017-03-15
公開日2018-09-19
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure and functional characterization of ElrR, a member of the RRNPP family of transcriptional regulators.
To be published
5V5U
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BU of 5v5u by Molmil
Crystal structure of leucine-rich protein regulator, ElrR, from Enterococcus faecalis
分子名称: Conserved domain protein
著者De Groote, M.C.R, Camargo, I.L, Serror, P, Horjales, E.
登録日2017-03-15
公開日2018-09-19
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Crystal structure of leucine-rich protein regulator, ElrR, from Enterococcus faecalis
To be published
5WFI
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BU of 5wfi by Molmil
X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
分子名称: FORMIC ACID, GLYCEROL, Ubiquitin, ...
著者Mesecar, A.D, Chen, Y.
登録日2017-07-12
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
To Be Published
3IXP
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BU of 3ixp by Molmil
Crystal structure of the ecdysone receptor bound to BYI08346
分子名称: Ecdysone receptor, Gene regulation protein, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ...
著者Moras, D, Billas, I.M.L, Browning, C.
登録日2009-09-04
公開日2010-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Adaptability of the ecdysone receptor bound to synthetic ligands
To be Published
5OK6
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BU of 5ok6 by Molmil
Ubiquitin specific protease 11 USP11 - peptide F complex
分子名称: 1,2-ETHANEDIOL, ALA-GLU-GLY-GLU-PHE-TYR-LYS-LEU-LYS-ILE-ARG-THR-PRO-AAR, GLYCEROL, ...
著者Spiliotopoulos, A, Dreveny, I.
登録日2017-07-25
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11.
J.Biol.Chem., 294, 2019
3LMN
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BU of 3lmn by Molmil
Oligomeric structure of the DUSP domain of human USP15
分子名称: ACETIC ACID, FORMIC ACID, Ubiquitin carboxyl-terminal hydrolase 15
著者Walker, J.R, Asinas, A, Avvakumov, G.V, Alenkin, D, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S.
登録日2010-01-31
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of the Human Ubiquitin-Specific Protease 15 DUSP Domain
To be Published
3OLQ
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BU of 3olq by Molmil
The crystal structure of a universal stress protein E from Proteus mirabilis HI4320
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Tan, K, Chhor, G, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-08-26
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.816 Å)
主引用文献The crystal structure of a universal stress protein E from Proteus mirabilis HI4320
To be Published
3PPA
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BU of 3ppa by Molmil
Structure of the Dusp-Ubl domains of Usp15
分子名称: CITRIC ACID, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 15
著者Walker, J.R, Asinas, A.E, Dong, A, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2010-11-24
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of the Dusp-Ubl Domains of the Ubiquitin-Specific Protease 15
To be Published
3PV1
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BU of 3pv1 by Molmil
Crystal structure of the USP15 DUSP-UBL domains
分子名称: ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15
著者Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L.
登録日2010-12-06
公開日2011-11-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Febs Lett., 585, 2011
8DH6
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BU of 8dh6 by Molmil
Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs
分子名称: CALCIUM ION, COPPER (II) ION, Cytochrome c oxidase subunit 1, ...
著者Godoy, A.S, Song, Y, Cheruvara, H, Quigley, A, Oliva, G.
登録日2022-06-25
公開日2022-07-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs
To Be Published
8DH7
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BU of 8dh7 by Molmil
Cryo-EM structure of Saccharomyces cerevisiae Succinyl-CoA:acetate CoA-transferase (Ach1p)
分子名称: Acetyl-CoA hydrolase
著者Godoy, A.S, Song, Y, Cheruvara, H, Quigley, A, Oliva, G.
登録日2022-06-25
公開日2022-07-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs
To Be Published
8DKT
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BU of 8dkt by Molmil
Crystal Structure of Septin1 - Septin2 heterocomplex from Drosophila melanogaster
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者de Freitas, A.F, Leonardo, D.A, Cavini, I.A, Pereira, H.M, Garratt, R.C.
登録日2022-07-06
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Conservation and divergence of the G-interfaces of Drosophila melanogaster septins.
Cytoskeleton (Hoboken), 80, 2023
8E25
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BU of 8e25 by Molmil
Crystal Structure of SARS-CoV-2 Main Protease M49I mutant in complex with Nirmatrelvir
分子名称: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab
著者Noske, G.D, Godoy, A.S, Oliva, G.
登録日2022-08-14
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease.
J.Biol.Chem., 299, 2023

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