5F3Z
 
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to PC-79-SH52 | | Descriptor: | 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, Genome polyprotein, ZINC ION | | Authors: | Noble, C.G. | | Deposit date: | 2015-12-03 | | Release date: | 2016-02-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening
J.Biol.Chem., 291, 2016
|
|
5EZM
 | | Crystal Structure of ArnT from Cupriavidus metallidurans in the apo state | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferases of PMT family, CHLORIDE ION, ... | | Authors: | Petrou, V.I, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2015-11-26 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation.
Science, 351, 2016
|
|
5FFR
 | | Crystal Structure of Surfactant Protein-A complexed with phosphocholine | | Descriptor: | CALCIUM ION, PHOSPHOCHOLINE, Pulmonary surfactant-associated protein A, ... | | Authors: | Goh, B.C, Wu, H, Rynkiewicz, M.J, Schulten, K, Seaton, B.A, McCormack, F.X. | | Deposit date: | 2015-12-18 | | Release date: | 2016-07-06 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Biochemistry, 55, 2016
|
|
6I1W
 | | Structure of the RNA duplex containing pseudouridine residue (5'-Gp(PSU)pC-3' sequence context) | | Descriptor: | RNA (5'-R(*AP*CP*UP*GP*AP*CP*UP*GP*A)-3'), RNA (5'-R(*UP*CP*AP*GP*(PSU)P*CP*AP*GP*U)-3') | | Authors: | Deb, I, Popenda, L, Sarzynska, J, Gdaniec, Z. | | Deposit date: | 2018-10-30 | | Release date: | 2019-11-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair.
Sci Rep, 9, 2019
|
|
4TSP
 | | Crystal structure of FraC with DHPC bound (crystal form II) | | Descriptor: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
6UE3
 | |
3USG
 | | Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles | | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, LEUCINE, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
|
|
3UJD
 | | Phosphoethanolamine methyltransferase mutant (Y19F) from Plasmodium falciparum in complex with phosphocholine | | Descriptor: | PHOSPHOCHOLINE, Phosphoethanolamine N-methyltransferase | | Authors: | Lee, S.G, Kim, Y, Alpert, T.D, Nagata, A, Jez, J.M. | | Deposit date: | 2011-11-07 | | Release date: | 2011-11-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target.
J.Biol.Chem., 287, 2012
|
|
3UJ9
 | | Phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with phosphocholine | | Descriptor: | PHOSPHOCHOLINE, Phosphoethanolamine N-methyltransferase | | Authors: | Lee, S.G, Kim, Y, Alpert, T.D, Nagata, A, Jez, J.M. | | Deposit date: | 2011-11-07 | | Release date: | 2011-11-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target.
J.Biol.Chem., 287, 2012
|
|
3USL
 | | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles | | Descriptor: | ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
|
|
3UJC
 | | Phosphoethanolamine methyltransferase mutant (H132A) from Plasmodium falciparum in complex with phosphocholine | | Descriptor: | PHOSPHOCHOLINE, Phosphoethanolamine N-methyltransferase | | Authors: | Lee, S.G, Kim, Y, Alpert, T.D, Nagata, A, Jez, J.M. | | Deposit date: | 2011-11-07 | | Release date: | 2011-11-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target.
J.Biol.Chem., 287, 2012
|
|
3USM
 | | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A) | | Descriptor: | IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.008 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
|
|
7LCH
 | | The mature Usutu SAAR-1776, Model B | | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Khare, B, Klose, T, Fang, Q, Kuhn, R. | | Deposit date: | 2021-01-11 | | Release date: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7LCG
 | | The mature Usutu SAAR-1776, Model A | | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Khare, B, Klose, T, Fang, Q, Kuhn, R. | | Deposit date: | 2021-01-11 | | Release date: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.42 Å) | | Cite: | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6VYM
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-18:1 nanodiscs treated with beta-cyclodextran | | Descriptor: | Mechanosensitive channel MscS | | Authors: | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | Deposit date: | 2020-02-27 | | Release date: | 2021-02-10 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
|
|
6VYL
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-10 nanodiscs | | Descriptor: | Mechanosensitive channel MscS | | Authors: | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | Deposit date: | 2020-02-27 | | Release date: | 2021-02-10 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
|
|
6VYK
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-18:1 nanodiscs | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mechanosensitive channel MscS | | Authors: | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | Deposit date: | 2020-02-27 | | Release date: | 2021-02-10 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
|
|
7RZF
 | | Insulin Degrading Enzyme O/pC | | Descriptor: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | | Authors: | Mancl, J.M, Liang, W.G, Tang, W.J. | | Deposit date: | 2021-08-27 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
|
|
7RZE
 | | Insulin Degrading Enzyme pO/pC | | Descriptor: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | | Authors: | Mancl, J.M, Liang, W.G, Tang, W.J. | | Deposit date: | 2021-08-27 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
|
|
7T7U
 | | Light Harvesting complex phycocyanin PC 630, from the cryptophyte Chroomonas sp. M1627 | | Descriptor: | DiCys-(15,16)-Dihydrobiliverdin, GLYCEROL, PHYCOCYANOBILIN, ... | | Authors: | Michie, K.A, Harrop, S.J, Rathbone, H.W, Wilk, K.E, Curmi, P.M.G. | | Deposit date: | 2021-12-15 | | Release date: | 2023-02-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins.
Protein Sci., 32, 2023
|
|
8JJ3
 | | Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 2.5 | | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel | | Authors: | Bharambe, N, Li, Z, Basak, S. | | Deposit date: | 2023-05-29 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.6476 Å) | | Cite: | Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.
Nat Commun, 15, 2024
|
|
8OVL
 | |
8OX9
 | | Cryo-EM structure of ATP8B1-CDC50A in E2P active conformation with bound PC | | Descriptor: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | | Deposit date: | 2023-05-01 | | Release date: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Activation and substrate specificity of the human P4-ATPase ATP8B1.
Nat Commun, 14, 2023
|
|
8OH7
 | |
8BEF
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core) | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | Authors: | Klusch, N, Kuehlbrandt, W. | | Deposit date: | 2022-10-21 | | Release date: | 2023-01-11 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (2.13 Å) | | Cite: | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
|
|
