3RBZ
 
 | | MthK channel, Ca2+-bound | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel mthK | | Authors: | Taylor, A.B, Parfenova, L.V, Rothberg, B.S. | | Deposit date: | 2011-03-30 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of multiple Ca2+-binding sites in a K+ channel RCK domain
Proc.Natl.Acad.Sci.USA, 2011
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7RYS
 | | SthK R120A Open State 2 | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C, Schmidpeter, P. | | Deposit date: | 2021-08-26 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7RSH
 | | SthK Y26F Closed State | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C. | | Deposit date: | 2021-08-11 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7RTF
 | | SthK R120A Closed State | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C. | | Deposit date: | 2021-08-13 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7RU0
 | | SthK R120A Open State 1 | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C, Schmidpeter, P. | | Deposit date: | 2021-08-16 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7RYR
 | | SthK R120A Open State 3 | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C, Schmidpeter, P. | | Deposit date: | 2021-08-26 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7RTJ
 | | SthK Y26F Activated State | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Gao, X, Nimigean, C. | | Deposit date: | 2021-08-13 | | Release date: | 2022-11-23 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
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7TKT
 | | SthK closed state, cAMP-bound in the presence of detergent | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | | Authors: | Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M. | | Deposit date: | 2022-01-17 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
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7TJ5
 | | SthK closed state, cAMP-bound in the presence of POPA | | Descriptor: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | | Authors: | Schmidpeter, P.A, Nimigean, C.M. | | Deposit date: | 2022-01-14 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (2.41 Å) | | Cite: | Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
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7TJ6
 | | SthK open state, cAMP-bound in the presence of POPA | | Descriptor: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | | Authors: | Schmidpeter, P.A, Nimigean, C.M. | | Deposit date: | 2022-01-14 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
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8DJB
 | | MthK-A90L mutant in closed state with 0 Ca2+ | | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | | Authors: | Agarwal, S, Nimigean, C.M. | | Deposit date: | 2022-06-30 | | Release date: | 2023-07-05 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Nat.Chem.Biol., 20, 2024
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3FB6
 | | KcsA Potassium channel in the partially open state with 16 A opening at T112 | | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | Deposit date: | 2008-11-18 | | Release date: | 2010-05-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | KcsA Potassium channel in the partially open state with 16 A opening at T112
TO BE PUBLISHED
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3F7Y
 | | KcsA Potassium channel in the partially open state with 17 A opening at T112 | | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | Deposit date: | 2008-11-10 | | Release date: | 2010-05-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | KcsA Potassium channel in the partially open state with 17 A opening at T112
TO BE PUBLISHED
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3F7V
 | | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 | | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment Heavy chain, ... | | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | Deposit date: | 2008-11-10 | | Release date: | 2010-05-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112
TO BE PUBLISHED
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6U6H
 | | Calcium-bound MthK open-inactivated state 3 | | Descriptor: | Calcium-gated potassium channel MthK | | Authors: | Chen, F, Crina, N. | | Deposit date: | 2019-08-29 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5R
 | | Calcium-bound MthK closed state | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5P
 | | Calcium-bound MthK gating ring state 1 | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U68
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6U6D
 | | MthK closed state with EDTA | | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | | Authors: | Fan, C, Rheinberger, J, Nimigean, C.M. | | Deposit date: | 2019-08-29 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5N
 | | Calcium-bound MthK gating ring state 2 | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U6E
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6UXB
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6UXA
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6VXZ
 | | SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | | Authors: | Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M. | | Deposit date: | 2020-02-25 | | Release date: | 2020-11-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
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6VY0
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