PDB: 37 resultsInfo pagesStatus searchChemie searchBIRD

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7CRW	Cryo-EM structure of rNLRP1-rDPP9 complex Descriptor: Dipeptidyl peptidase 9, NLR family protein 1 Authors: Huang, M.H, Zhang, X.X, Wang, J, Chai, J.J. Deposit date: 2020-08-14 Release date: 2021-03-24 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural and biochemical mechanisms of NLRP1 inhibition by DPP9. Nature, 592, 2021
6X6A	Cryo-EM structure of NLRP1-DPP9 complex Descriptor: Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1 Authors: Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H. Deposit date: 2020-05-27 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature, 592, 2021
6X6C	Cryo-EM structure of NLRP1-DPP9-VbP complex Descriptor: Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1, ... Authors: Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H. Deposit date: 2020-05-27 Release date: 2021-03-10 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature, 592, 2021
6NPY	Cryo-EM structure of NLRP3 bound to NEK7 Descriptor: ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 3, ... Authors: Sharif, H, Wang, L, Wang, W.L, Wu, H. Deposit date: 2019-01-18 Release date: 2019-06-19 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature, 570, 2019
5YUD	Flagellin derivative in complex with the NLR protein NAIP5 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1e, Phase 2 flagellin,Flagellin Authors: Yang, X.R, Yang, F, Wang, W.G, Lin, G.Z. Deposit date: 2017-11-21 Release date: 2018-01-03 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.28 Å) Cite: Structural basis for specific flagellin recognition by the NLR protein NAIP5. Cell Res., 28, 2018
6B5B	Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome Descriptor: Baculoviral IAP repeat-containing protein 1e, Flagellin, NLR family CARD domain-containing protein 4 Authors: Tenthorey, J.L, Haloupek, N, Lopez-Blanco, J.R, Grob, P, Adamson, E, Hartenian, E, Lind, N.A, Bourgeois, N.M, Chacon, P, Nogales, E, Vance, R.E. Deposit date: 2017-09-29 Release date: 2017-11-15 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science, 358, 2017
5IRN	Crystal structure of rabbit NOD2 in an ADP-bound state (Crystal form1) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Uncharacterized protein Authors: Maekawa, S, Ohto, U, Shimizu, T. Deposit date: 2016-03-14 Release date: 2016-06-29 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of NOD2 and its implications in human disease. Nat Commun, 7, 2016
5IRM	Crystal structure of rabbit NOD2 in an ADP-bound state (Crystal form2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Uncharacterized protein Authors: Maekawa, S, Ohto, U, Shimizu, T. Deposit date: 2016-03-14 Release date: 2016-06-29 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Crystal structure of NOD2 and its implications in human disease. Nat Commun, 7, 2016
5IRL	Crystal structure of rabbit NOD2 SER mutant in an ADP-bound state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Uncharacterized protein Authors: Maekawa, S, Ohto, U, Shimizu, T. Deposit date: 2016-03-14 Release date: 2016-06-29 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Crystal structure of NOD2 and its implications in human disease. Nat Commun, 7, 2016
3JBL	Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization Descriptor: NLR family CARD domain-containing protein 4 Authors: Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. Deposit date: 2015-09-05 Release date: 2015-10-21 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science, 350, 2015
5AJ2	Cryo electron tomography of the Naip5-Nlrc4 inflammasome Descriptor: NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 Authors: Diebolder, C.A, Halff, E.F, Koster, A.J, Huizinga, E.G, Koning, R.I. Deposit date: 2015-02-20 Release date: 2015-11-11 Last modified: 2017-08-23 Method: ELECTRON MICROSCOPY (40 Å) Cite: Cryoelectron Tomography of the Naip5/Nlrc4 Inflammasome: Implications for Nlr Activation. Structure, 23, 2015
4KXF	Crystal structure of NLRC4 reveals its autoinhibition mechanism Descriptor: ADENOSINE-5'-DIPHOSPHATE, NLR family CARD domain-containing protein 4, SULFATE ION Authors: Chai, J, Hu, Z. Deposit date: 2013-05-25 Release date: 2013-07-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of NLRC4 reveals its autoinhibition mechanism Science, 341, 2013

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