8C24
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8C26
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7YCU
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7YCS
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7R5A
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7ETR
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6XRW
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![BU of 6xrw by Molmil](/molmil-images/mine/6xrw) | Chromosomal ParDE TA system from P. aeruginosa | Descriptor: | BENZAMIDINE, GLYCEROL, NONAETHYLENE GLYCOL, ... | Authors: | Bourne, C.R, Snead, K.J, Thomas, L.M. | Deposit date: | 2020-07-13 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kinetics. Biochemistry, 61, 2022
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6X0A
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![BU of 6x0a by Molmil](/molmil-images/mine/6x0a) | X-ray structure of a chimeric ParDE toxin-antitoxin complex from Mesorhizobium opportunistum | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Plasmid stabilization system, Putative addiction module antidote protein, ... | Authors: | Lite, T.L, Grant, R.A, Laub, M.T. | Deposit date: | 2020-05-15 | Release date: | 2020-11-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library. Elife, 9, 2020
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5CZF
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5CZE
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5CW7
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5CEG
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![BU of 5ceg by Molmil](/molmil-images/mine/5ceg) | X-ray structure of toxin/anti-toxin complex from Mesorhizobium opportunistum | Descriptor: | Addiction module antidote protein, CopG/Arc/MetJ family, GLYCEROL, ... | Authors: | Aakre, C.D, Herrou, J, Crosson, S, Laub, M.T. | Deposit date: | 2015-07-06 | Release date: | 2015-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates. Cell, 163, 2015
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4NRN
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![BU of 4nrn by Molmil](/molmil-images/mine/4nrn) | Crystal structure of metal-bound toxin from Helicobacter pylori | Descriptor: | ZINC ION, metal-bound toxin | Authors: | Lee, B.J, Im, H, Pathak, C, Jang, S.B. | Deposit date: | 2013-11-27 | Release date: | 2014-10-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Crystal structure of toxin HP0892 from Helicobacter pylori with two Zn(II) at 1.8 angstrom resolution Protein Sci., 23, 2014
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4LSY
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![BU of 4lsy by Molmil](/molmil-images/mine/4lsy) | Crystal structure of copper-bound L66S mutant toxin from Helicobacter pylori | Descriptor: | CITRATE ANION, COPPER (II) ION, Uncharacterized protein, ... | Authors: | Lee, B.J, Im, H, Pathak, C.C, Yoon, H.J. | Deposit date: | 2013-07-23 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.895 Å) | Cite: | Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity Biochim.Biophys.Acta, 1834, 2013
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4LTT
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![BU of 4ltt by Molmil](/molmil-images/mine/4ltt) | Crystal structure of native apo toxin from Helicobacter pylori | Descriptor: | Uncharacterized protein, toxin | Authors: | Lee, B.J, Im, H, Pathak, C.C, Yoon, H.J. | Deposit date: | 2013-07-23 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity Biochim.Biophys.Acta, 1834, 2013
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4LS4
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![BU of 4ls4 by Molmil](/molmil-images/mine/4ls4) | Crystal structure of L66S mutant toxin from Helicobacter pylori | Descriptor: | BROMIDE ION, Uncharacterized protein, Toxin | Authors: | Pathak, C.C, Im, H, Lee, B.J, Yoon, H.J. | Deposit date: | 2013-07-22 | Release date: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity Biochim.Biophys.Acta, 1834, 2013
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4FXE
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4FXI
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4FXH
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3KXE
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4V7K
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![BU of 4v7k by Molmil](/molmil-images/mine/4v7k) | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | Deposit date: | 2009-11-02 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
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4V7J
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![BU of 4v7j by Molmil](/molmil-images/mine/4v7j) | Structure of RelE nuclease bound to the 70S ribosome (precleavage state) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | Deposit date: | 2009-11-02 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
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2KHE
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![BU of 2khe by Molmil](/molmil-images/mine/2khe) | Solution Structure of the Bacterial Toxin Rele from Thermus Thermophilus HB8 | Descriptor: | Toxin-like protein | Authors: | Suzuki, S, Kawazoe, M, Kaminishi, T, Takemoto, C, Muto, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-04-03 | Release date: | 2010-03-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Bacterial Toxin Rele from Thermus Thermophilus HB8 To be Published
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3G5O
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![BU of 3g5o by Molmil](/molmil-images/mine/3g5o) | The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2009-02-05 | Release date: | 2009-04-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes. Structure, 21, 2013
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2KC8
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![BU of 2kc8 by Molmil](/molmil-images/mine/2kc8) | Structure of E. coli toxin RelE (R81A/R83A) mutant in complex with antitoxin RelBc (K47-L79) peptide | Descriptor: | Antitoxin RelB, Toxin relE | Authors: | Li, G, Zhang, Y, Inouye, M, Ikura, M. | Deposit date: | 2008-12-17 | Release date: | 2009-03-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin module involves a helix displacement near an mRNA interferase active site. J.Biol.Chem., 284, 2009
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