PDB: 322 resultsInfo pagesStatus searchChemie searchBIRD

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4ZH2	Crystal structure of Escherichia coli RNA polymerase in complex with CBR703 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Feng, Y, Ebright, R.H. Deposit date: 2015-04-24 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.204 Å) Cite: Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
4ZH3	Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Feng, Y, Ebright, R.H. Deposit date: 2015-04-24 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.082 Å) Cite: Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
4ZH4	Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18 Descriptor: 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Feng, Y, Ebright, R.H. Deposit date: 2015-04-24 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.993 Å) Cite: Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
6N60	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. Deposit date: 2018-11-23 Release date: 2019-01-09 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.68 Å) Cite: Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6OMF	CryoEM structure of SigmaS-transcription initiation complex with activator Crl Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. Deposit date: 2019-04-18 Release date: 2019-08-28 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
6OY7	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OVY	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.999 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY5	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OW3	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-09 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.766 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY6	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.096 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OUL	Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-05-04 Release date: 2020-02-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6OVR	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.843 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6P1K	Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-05-20 Release date: 2020-02-26 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6P18	Q21 transcription antitermination complex: loading complex Descriptor: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2019-05-19 Release date: 2019-06-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
6PMJ	Sigm28-transcription initiation complex with specific promoter at the state 2 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Liu, B, Shi, W. Deposit date: 2019-07-02 Release date: 2020-05-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.91 Å) Cite: Structural basis of bacterial sigma28-mediated transcription reveals roles of the RNA polymerase zinc-binding domain. Embo J., 39, 2020
6P70	X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-06-04 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.052 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.35 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PFJ	Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor Authors: Schumacher, M.A. Deposit date: 2019-06-21 Release date: 2019-11-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.08 Å) Cite: c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
6P71	X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*GP*CP*CP*GP*GP*GP*A)-3'), DNA (5'-D(P*CP*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-06-04 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2021-10-20 Method: ELECTRON MICROSCOPY (4.29 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PFV	Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor Authors: Schumacher, M.A. Deposit date: 2019-06-22 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3 Å) Cite: c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
6PMI	Sigm28-transcription initiation complex with specific promoter at the state 1 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Liu, B, Shi, W. Deposit date: 2019-07-02 Release date: 2020-05-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Structural basis of bacterial sigma28-mediated transcription reveals roles of the RNA polymerase zinc-binding domain. Embo J., 39, 2020
6PSU	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSR	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020

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