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6PDT	cryoEM structure of yeast glucokinase filament Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glucokinase-1, MAGNESIUM ION, ... Authors: Lynch, E.M, Dosey, A.M, Farrell, D.P, Stoddard, P.R, Kollman, J.M. Deposit date: 2019-06-19 Release date: 2020-03-11 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Science, 367, 2020
6R2N	Crystal structure of KlGlk1 glucokinase from Kluyveromyces lactis Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, Glucokinase-1 Authors: Zak, K, Wator, E, Grudnik, P. Deposit date: 2019-03-18 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.596 Å) Cite: Crystal Structure of Kluyveromyces lactis Glucokinase ( Kl Glk1). Int J Mol Sci, 20, 2019
6VYF	Cryo-EM structure of Plasmodium vivax hexokinase (Open state) Descriptor: Phosphotransferase Authors: Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S. Deposit date: 2020-02-26 Release date: 2020-05-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures Iucrj, 7, 2020
6VYG	Cryo-EM structure of Plasmodium vivax hexokinase (Closed state) Descriptor: Phosphotransferase Authors: Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S. Deposit date: 2020-02-26 Release date: 2020-05-06 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures Iucrj, 7, 2020
7T78	CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND DIETHYL ({2-[3-(4-METHANESULFONYLPHENO XY)-5-{[(2S)-1-METHOXYPROPAN-2-YL]OXY}BENZAMIDO]-1,3-THIAZ OL-4-YL}METHYL)PHOSPHONATE Descriptor: 1,2-ETHANEDIOL, Isoform 2 of Hexokinase-4, SODIUM ION, ... Authors: Muckelbauer, J.K. Deposit date: 2021-12-14 Release date: 2022-03-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132). J.Med.Chem., 65, 2022
7T79	CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND AKA DIETHYL {[3-(3-{[5-(AZETIDINE-1-CARBON YL)PYRAZIN-2-YL]OXY}-5-(PROPAN-2-YLOXY)BENZAMIDO)-1H- PYRAZOL-1-YL]METHYL}PHOSPHONATE Descriptor: Isoform 2 of Hexokinase-4, alpha-D-glucopyranose, diethyl {[3-(3-{[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy}-5-[(propan-2-yl)oxy]benzamido)-1H-pyrazol-1-yl]methyl}phosphonate Authors: Muckelbauer, J.K. Deposit date: 2021-12-14 Release date: 2022-03-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132). J.Med.Chem., 65, 2022
7ZZI	Plasmodium falciparum hexokinase complexed with glucose and citrate Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ... Authors: Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K. Deposit date: 2022-05-25 Release date: 2023-08-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion. Int J Mol Sci, 24, 2023

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