8IIS
| MsmUdgX H109S/R184A double mutant | 分子名称: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIO
| H109Q mutant of uracil DNA glycosylase X | 分子名称: | GLYCEROL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIN
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8IIM
| H109K mutant of uracil DNA glycosylase X | 分子名称: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIP
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8IIF
| H109A mutant of uracil DNA glycosylase X | 分子名称: | GLYCEROL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIT
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8IIL
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8IIJ
| H109G mutant of uracil DNA glycosylase X | 分子名称: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIE
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8IIQ
| MsmUdgX H109S/E52N double mutant | 分子名称: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIG
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8IIR
| MsmUdgX H109S/Q53A double mutant | 分子名称: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8III
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8IIH
| H109C mutant of uracil DNA glycosylase X | 分子名称: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | 著者 | Aroli, S. | 登録日 | 2023-02-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8I67
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 2,4-Thiazolidinedione, Form I | 分子名称: | 1,2-ETHANEDIOL, 1,3-thiazolidine-2,4-dione, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I63
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form III | 分子名称: | 1,2-ETHANEDIOL, BARBITURIC ACID, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I6B
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Hydroxy-2,4(1H,3H)-pyrimidinedione, Form I | 分子名称: | 1,2-ETHANEDIOL, 5-oxidanyl-1~{H}-pyrimidine-2,4-dione, CHLORIDE ION, ... | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I61
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid and Citric acid, Form I | 分子名称: | 1,2-ETHANEDIOL, BARBITURIC ACID, CITRIC ACID, ... | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I66
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid) and citric acid, Form I | 分子名称: | 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, CITRIC ACID, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I65
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid), Form I | 分子名称: | 1,2-ETHANEDIOL, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I68
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Uric acid, Form III | 分子名称: | 1,2-ETHANEDIOL, URIC ACID, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I6A
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Orotic acid, Form III | 分子名称: | 1,2-ETHANEDIOL, OROTIC ACID, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I64
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form II | 分子名称: | 1,2-ETHANEDIOL, BARBITURIC ACID, Uracil-DNA glycosylase | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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8I62
| Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form I | 分子名称: | 1,2-ETHANEDIOL, BARBITURIC ACID, CHLORIDE ION, ... | 著者 | Raj, P, Paul, A, Gopal, B. | 登録日 | 2023-01-27 | 公開日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment Eur.J.Med.Chem., 258, 2023
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