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8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
Descriptor: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
Deposit date:2023-01-06
Release date:2023-09-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GXM
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BU of 6gxm by Molmil
Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-22
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
4AC9
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BU of 4ac9 by Molmil
CRYSTAL STRUCTURE OF TRANSLATION ELONGATION FACTOR SELB FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH GDP
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Leibundgut, M, Frick, C, Thanbichler, M, Boeck, A, Ban, N.
Deposit date:2011-12-14
Release date:2012-08-22
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Selenocysteine tRNA-Specific Elongation Factor Selb is a Structural Chimaera of Elongation and Initiation Factors.
Embo J., 24, 2005
6GXO
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BU of 6gxo by Molmil
Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and P/E-tRNA (State IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GQB
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BU of 6gqb by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6GWT
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BU of 6gwt by Molmil
Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-25
Release date:2018-08-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6FF4
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BU of 6ff4 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2018-08-29
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
8FZD
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BU of 8fzd by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZI
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BU of 8fzi by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8EUB
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BU of 8eub by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-18
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVR
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BU of 8evr by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
Descriptor: (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVQ
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BU of 8evq by Molmil
Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVS
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BU of 8evs by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWB
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BU of 8ewb by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-22
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8FZF
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BU of 8fzf by Molmil
Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe (Composite state I-C)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-06-26
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZG
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BU of 8fzg by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
3ZZT
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BU of 3zzt by Molmil
Crystal structure of Staphylococcus aureus elongation factor G with a fusidic-acid-resistant mutation F88L
Descriptor: ELONGATION FACTOR G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Elongation Factor-G-Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
3ZZU
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BU of 3zzu by Molmil
Crystal structure of Staphylococcus aureus elongation factor G with mutations M16I and F88L
Descriptor: ELONGATION FACTOR G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Mechanism of Elongation Factor-G Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
3J0E
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BU of 3j0e by Molmil
Models for the T. thermophilus ribosome recycling factor and the E. coli elongation factor G bound to the E. coli post-termination complex
Descriptor: 30S ribosomal protein S12, Elongation factor G, Ribosome-recycling factor, ...
Authors:Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K.
Deposit date:2011-06-29
Release date:2012-04-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-15
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G60
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BU of 8g60 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
3IZP
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BU of 3izp by Molmil
Conformation of EF-G during translocation
Descriptor: Elongation factor G
Authors:Li, W, Trabuco, L.G, Schulten, K, Frank, J.
Deposit date:2010-11-15
Release date:2011-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY
Cite:Molecular dynamics of EF-G during translocation.
Proteins, 79, 2011
3ZZ0
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BU of 3zz0 by Molmil
Crystal structure of ribosomal elongation factor (EF)-G from Staphylococcus aureus with a fusidic acid hyper-sensitivity mutation M16I
Descriptor: Elongation factor G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-08-30
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus.
J. Biol. Chem., 287, 2012

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