PDB: 83 件ウェブページステータス検索Chemie searchBIRD

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4XTV	Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 36 (N-({[(1R,3S)-3-(6-amino-9H-purin-9-yl)cyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide) 分子名称: Bifunctional ligase/repressor BirA, N-({[(1R,3S)-3-(6-amino-9H-purin-9-yl)cyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide 著者 De la Mora-Rey, T, Finzel, B.C. 登録日 2015-01-24 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45000839 Å) 主引用文献 Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. J.Med.Chem., 58, 2015
4XU1	Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 82 that incorporates a morpholine in place of the ribose 分子名称: 1,2-ETHANEDIOL, Bifunctional ligase/repressor BirA, DIMETHYL SULFOXIDE, ... 著者 De la Mora-Rey, T, Finzel, B.C. 登録日 2015-01-24 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.70001328 Å) 主引用文献 Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. J.Med.Chem., 58, 2015
4XU3	Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 90 that has an acyclic ether in place of the ribose 分子名称: Bifunctional ligase/repressor BirA, CHLORIDE ION, N-({2-[(6-amino-9H-purin-9-yl)methoxy]ethyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide 著者 De la Mora-Rey, T, Finzel, B.C. 登録日 2015-01-24 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.242677 Å) 主引用文献 Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. J.Med.Chem., 58, 2015
4WF2	Structure of E. coli BirA G142A bound to biotinol-5'-AMP 分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Bifunctional ligase/repressor BirA 著者 Eginton, C, Beckett, D, Wade, H. 登録日 2014-09-11 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Allosteric Coupling via Distant Disorder-to-Order Transitions. J.Mol.Biol., 427, 2015
4TVW	Resorufin ligase with bound resorufin-AMP analog 分子名称: 5'-O-{[5-(7-hydroxy-3-oxo-3H-phenoxazin-2-yl)pentanoyl]sulfamoyl}adenosine, Lipoate-protein ligase A 著者 Goldman, P.J, Drennan, C.L. 登録日 2014-06-28 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.505 Å) 主引用文献 Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc.Natl.Acad.Sci.USA, 111, 2014
4TVY	Apo resorufin ligase 分子名称: 5-(3,7-dihydroxy-10H-phenoxazin-2-yl)pentanamide, Lipoate-protein ligase A 著者 Goldman, P.J, Drennan, C.L. 登録日 2014-06-28 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc.Natl.Acad.Sci.USA, 111, 2014
4OP0	Crystal structure of biotin protein ligase (RV3279C) of Mycobacterium tuberculosis, complexed with biotinyl-5'-AMP 分子名称: BIOTINYL-5-AMP, BirA bifunctional protein, SULFATE ION 著者 Ma, Q, Wilmanns, M, Akhter, Y. 登録日 2014-02-04 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis. Protein Sci., 23, 2014
3RUX	Crystal structure of biotin-protein ligase BirA from Mycobacterium tuberculosis in complex with an acylsulfamide bisubstrate inhibitor 分子名称: 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, BirA bifunctional protein 著者 Geders, T.W, Finzel, B.C. 登録日 2011-05-05 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis. Chem.Biol., 18, 2011
3R07	Structural analysis of an archaeal lipoylation system. A bi-partite lipoate protein ligase and its E2 lipoyl domain from Thermoplasma acidophilum 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Lipoate-protein ligase A subunit 1, ... 著者 Posner, M.G, Upadhyay, U, Crennell, S. 登録日 2011-03-07 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural analysis of an archaeal lipoylation system. A bi-partite lipoate protein ligase and its E2 lipoyl domain from Thermoplasma acidophilum To be Published
3L2Z	Crystal structure of hydrated Biotin Protein Ligase from M. tuberculosis 分子名称: BirA bifunctional protein 著者 Gupta, V, Gupta, R.K, Khare, G, Salunke, D.M, Tyagi, A.K. 登録日 2009-12-16 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration. Plos One, 5, 2010
3L1A	Structural ordering of disordered ligand binding loops of biotin protein ligase into active conformations as a consequence of dehydration 分子名称: BirA bifunctional protein 著者 Gupta, V. 登録日 2009-12-11 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration. Plos One, 5, 2010
3A7R	Crystal structure of E. coli lipoate-protein ligase A in complex with lipoyl-AMP. 分子名称: 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, Lipoate-protein ligase A, MAGNESIUM ION, ... 著者 Fujiwara, K, Hosaka, H. 登録日 2009-10-01 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Global conformational change associated with the two-step reaction catalyzed by Escherichia coli lipoate-protein ligase A. J.Biol.Chem., 285, 2010
3A7A	Crystal structure of E. coli lipoate-protein ligase A in complex with octyl-amp and apoH-protein 分子名称: ADENOSINE MONOPHOSPHATE, Glycine cleavage system H protein, Lipoate-protein ligase A, ... 著者 Fujiwara, K, Hosaka, H, Nakagawa, A. 登録日 2009-09-20 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Global conformational change associated with the two-step reaction catalyzed by Escherichia coli lipoate-protein ligase A. J.Biol.Chem., 285, 2010
3FJP	Apo structure of Biotin protein ligase from Aquifex aeolicus 分子名称: Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION 著者 McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J. 登録日 2008-12-15 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
3EFR	Biotin protein ligase R40G mutant from Aquifex aeolicus in complex with biotin 分子名称: BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION 著者 Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. 登録日 2008-09-10 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
3EFS	Biotin protein ligase from Aquifex aeolicus in complex with biotin and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, ... 著者 Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. 登録日 2008-09-10 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
2ZGW	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Adenosine and Biotin, Mutations R48A and K111A 分子名称: ADENOSINE, BIOTIN, biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-01-28 公開日 2008-02-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
2EJG	Crystal Structure Of The Biotin Protein Ligase (Mutation R48A) and Biotin Carboxyl Carrier Protein Complex From Pyrococcus Horikoshii OT3 分子名称: 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE, ... 著者 Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-16 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
2EJF	Crystal Structure Of The Biotin Protein Ligase (Mutations R48A and K111A) and Biotin Carboxyl Carrier Protein Complex From Pyrococcus Horikoshii OT3 分子名称: 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE, ... 著者 Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-16 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
2EJ9	Crystal Structure Of Biotin Protein Ligase From Methanococcus jannaschii 分子名称: BIOTIN, Putative biotin ligase 著者 Bagautdinov, B, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-16 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure Of Biotin Protein Ligase From Methanococcus jannaschii To be Published
2P5I	Crystal structure of protein BH3822 from Bacillus halodurans, a member of the biotin/lipoate A/B protein ligase family 分子名称: BH3822 protein 著者 Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-03-15 公開日 2007-03-27 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of a hypothetical protein from Bacillus halodurans: Pfam-PF03099 To be Published
2EAY	Crystal Structure Of Biotin Protein Ligase From Aquifex Aeolicus 分子名称: Biotin [acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-04 公開日 2007-08-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure Of Biotin Protein Ligase From Aquifex Aeolicus To be Published
2E65	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3, Mutation D104A 分子名称: biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-12-25 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 To be Published
2E64	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii, Mutations R48A and K111A 分子名称: biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-12-25 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
2E41	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with the Reaction Product Analog Biotinol-5'-AMP, Mutations R48A and K111A 分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-12-01 公開日 2007-06-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008

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