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2MGY
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Solution structure of the mitochondrial translocator protein (TSPO) in complex with its high-affinity ligand PK11195
分子名称: N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, Translocator protein
著者Jaremko, M, Jaremko, L, Giller, K, Becker, S, Zweckstetter, M.
登録日2013-11-11
公開日2014-04-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of the mitochondrial translocator protein in complex with a diagnostic ligand.
Science, 343, 2014
2N02
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BU of 2n02 by Molmil
Solution structure of the A147T variant of the mitochondrial translocator protein (tspo) in complex with pk11195
分子名称: N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, Translocator protein
著者Jaremko, M, Jaremko, L, Giller, K, Becker, S, Zweckstetter, M.
登録日2015-03-04
公開日2015-06-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Integrity of the A147T Polymorph of Mammalian TSPO.
Chembiochem, 16, 2015
4RYI
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BU of 4ryi by Molmil
Crystal structure of BcTSPO/PK11195 complex
分子名称: Integral membrane protein, N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-15
公開日2015-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYJ
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BU of 4ryj by Molmil
Crystal structure of apo dimer of BcTSPO
分子名称: Integral membrane protein
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-15
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYM
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BU of 4rym by Molmil
Crystal structure of BcTSPO Iodo Type1 monomer
分子名称: IODIDE ION, Integral membrane protein
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-15
公開日2015-01-28
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYN
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BU of 4ryn by Molmil
Crystal structure of BcTSPO, type1 monomer
分子名称: CACODYLATE ION, DODECYL-ALPHA-D-MALTOSIDE, Integral membrane protein, ...
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-15
公開日2015-02-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYO
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BU of 4ryo by Molmil
Crystal structure of BcTSPO type II high resolution monomer
分子名称: DIMETHYL SULFOXIDE, Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-15
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYQ
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BU of 4ryq by Molmil
Crystal structure of BcTSPO, type 2 at 1.7 Angstrom
分子名称: Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-16
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4RYR
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BU of 4ryr by Molmil
Crystal structure of BcTSPO, type 2 at 1.7 Angstrom with DMSO
分子名称: DIMETHYL SULFOXIDE, Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
著者Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-12-16
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.704 Å)
主引用文献Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
4UC1
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BU of 4uc1 by Molmil
High resolution crystal structure of translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, METHOXY-ETHOXYL, ...
著者Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
登録日2014-08-13
公開日2015-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
4UC2
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BU of 4uc2 by Molmil
Crystal structure of translocator protein 18kDa (TSPO) from rhodobacter sphaeroides (A139T mutant) in P212121 space group
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TETRAETHYLENE GLYCOL, TRANSLOCATOR PROTEIN TSPO
著者Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
登録日2014-08-13
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
4UC3
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BU of 4uc3 by Molmil
Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO
著者Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
登録日2014-08-13
公開日2015-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
5DUO
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BU of 5duo by Molmil
Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ...
著者Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
登録日2015-09-20
公開日2015-11-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350, 2015
8E7W
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BU of 8e7w by Molmil
RsTSPO A139T with Heme
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
8E7X
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BU of 8e7x by Molmil
RsTSPO A138F with one Heme bound
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
8E7Y
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BU of 8e7y by Molmil
RsTSPO A138F with two heme bound
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
8E7Z
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BU of 8e7z by Molmil
RsTSPO mutant -A138F
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023

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件を2024-05-01に公開中

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