PDB: 91 resultsInfo pagesStatus searchChemie searchBIRD

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6MV9	X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase, ... Authors: Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. Deposit date: 2018-10-24 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
6MVE	Reduced X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. Deposit date: 2018-10-25 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
6MYX	EM structure of Bacillus subtilis ribonucleotide reductase inhibited double-helical filament of NrdE alpha subunit with dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase Authors: Thomas, W.C, Bacik, J.P, Chen, J.Z, Ando, N. Deposit date: 2018-11-02 Release date: 2019-06-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6 Å) Cite: Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
6MW3	EM structure of Bacillus subtilis ribonucleotide reductase inhibited filament composed of NrdE alpha subunit and NrdF beta subunit with dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase, Ribonucleoside-diphosphate reductase NrdF beta subunit Authors: Thomas, W.C, Bacik, J.P, Kaelber, J.T, Ando, N. Deposit date: 2018-10-29 Release date: 2019-06-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.65 Å) Cite: Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
2BQ1	Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, FE (III) ION, MAGNESIUM ION, ... Authors: Uppsten, M, Farnegardh, M, Domkin, V, Uhlin, U. Deposit date: 2005-04-26 Release date: 2006-05-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.99 Å) Cite: The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into its Mechanism of Action J.Mol.Biol., 359, 2006
3PAW	Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Fairman, J.W, Wijerathna, S.R, Dealwis, C.G. Deposit date: 2010-10-19 Release date: 2011-02-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (6.61 Å) Cite: Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
2CVU	Structures of Yeast Ribonucleotide Reductase I Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVX	Structures of Yeast Ribonucleotide Reductase I Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY	Structures of Yeast Ribonucleotide Reductase I Descriptor: 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW	Structures of Yeast Ribonucleotide Reductase I Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
1XJE	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-10-11 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJM	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP complex Descriptor: MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJK	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-11-22 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJF	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJG	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-UDP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
1XJJ	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2005
1XJN	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-CDP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
3R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN Authors: Eriksson, M, Eklund, H. Deposit date: 1997-07-21 Release date: 1998-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
3RSR	Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 Authors: Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G. Deposit date: 2011-05-02 Release date: 2012-11-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol.Cancer Ther., 11, 2012
2EUD	Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides Descriptor: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J. Deposit date: 2005-10-28 Release date: 2006-03-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
3S8B	Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S8A	Structure of Yeast Ribonucleotide Reductase R293A with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published

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