PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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8FW6	Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336 分子名称: (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... 著者 Lowther, W.T, Gumpena, R. 登録日 2023-01-20 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Human Lactate Dehydrogenase A in complex with inhibitor CHK-336 To Be Published
8GGH	Structure of Trypanosoma (MDH)4-PEX5, distal conformation 分子名称: Peroxisome targeting signal 1 receptor, malate dehydrogenase 著者 Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. 登録日 2023-03-08 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Structure of Trypanosoma (MDH)4-PEX5, distal conformation To Be Published
4UUN	Trichomonas vaginalis lactate dehydrogenase in complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4UUO	Apo Trichomonas vaginalis malate dehydrogenase 分子名称: CYTOSOLIC MALATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.842 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4WLF	Crystal structure of L-malate bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-malate bound MDH2 To Be Published
4WLN	Crystal structure of apo MDH2 分子名称: Malate dehydrogenase, mitochondrial, PHOSPHATE ION 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of apo MDH2 To Be Published
4WLE	Crystal structure of citrate bound MDH2 分子名称: CITRIC ACID, Malate dehydrogenase, mitochondrial 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of citrate bound MDH2 To Be Published
4WLV	Crystal structure of NAD bound MDH2 分子名称: Malate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-08 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of NAD bound MDH2 To Be Published
8GH2	Structure of Trypanosoma (MDH)4-(Pex5)2, close conformation 分子名称: Peroxisome targeting signal 1 receptor, malate dehydrogenase 著者 Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. 登録日 2023-03-09 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structure of Trypanosoma (MDH)4-(Pex5)2, close conformation To Be Published
8GGD	Structure of Trypanosoma (MDH)4-Pex5, close conformation 分子名称: Peroxisome targeting signal 1 receptor, malate dehydrogenase 著者 Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. 登録日 2023-03-08 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structure of Trypanosoma (MDH)4-Pex5, close conformation To Be Published
8GH3	Structure of Trypanosoma (MDH)4-(Pex5)2, distal conformation 分子名称: Peroxisome targeting signal 1 receptor, malate dehydrogenase 著者 Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. 登録日 2023-03-09 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structure of Trypanosoma (MDH)4-(Pex5)2, distal conformation To Be Published
4WLU	Crystal structure of L-malate and NAD bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-08 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal structure of L-malate and NAD bound MDH2 To Be Published
8GI0	Structure of Trypanosoma docking complex 分子名称: Peroxisomal membrane protein PEX14, Peroxisome targeting signal 1 receptor, malate dehydrogenase 著者 Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. 登録日 2023-03-13 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of Trypanosoma docking complex To Be Published
4WLO	Crystal structure of oxaloacetate and NADH bound MDH2 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of oxaloacetate and NADH bound MDH2 To Be Published
8J5D	Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH 分子名称: Beta-amylase 1, chloroplastic, Malate dehydrogenase, ... 著者 Guan, Z.Y, Liu, J, Yan, J.J. 登録日 2023-04-21 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation. Plant Cell, 36, 2023
8LDH	REFINED CRYSTAL STRUCTURE OF DOGFISH M4 APO-LACTATE DEHYDROGENASE 分子名称: CITRIC ACID, M4 APO-LACTATE DEHYDROGENASE 著者 Abad-Zapatero, C, Rossmann, M.G. 登録日 1988-01-04 公開日 1989-07-12 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Refined crystal structure of dogfish M4 apo-lactate dehydrogenase. J.Mol.Biol., 198, 1987
6OR9	Structure of L-lactate dehydrogenase from Trichoplusia ni 分子名称: L-lactate dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-04-29 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of L-lactate dehydrogenase from Trichoplusia ni to be published
6P6U	Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit 分子名称: ADENOSINE MONOPHOSPHATE, L-lactate dehydrogenase A chain 著者 McPherson, A. 登録日 2019-06-04 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit to be published
6PBL	Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 分子名称: Malate dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-06-14 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 TO BE PUBLISHED
6Q0D	CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00384414-01 AT 2.05 A RESOLUTION 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ... 著者 Dranow, D.M, Davies, D.R. 登録日 2019-08-01 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J.Med.Chem., 63, 2020
6Q13	CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, ... 著者 Davies, D.R, Dranow, D.M. 登録日 2019-08-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J.Med.Chem., 63, 2020
6QSS	Crystal Structure of Ignicoccus islandicus malate dehydrogenase co-crystallized with 10 mM Tb-Xo4 分子名称: CHLORIDE ION, Malate dehydrogenase, TERBIUM(III) ION, ... 著者 Roche, J, Girard, E, Madern, D. 登録日 2019-02-21 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 SOLUTION SCATTERING (1.892 Å), X-RAY DIFFRACTION 主引用文献 The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization. J.Struct.Biol., 208, 2019
6R8G	Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine 分子名称: 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M. 登録日 2019-04-01 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Fragment-Based Approach Identifies an Allosteric Pocket that Impacts Malate Dehydrogenase Activity Commun Biol, 2021
6SBU	X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3) 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid, L-lactate dehydrogenase A chain 著者 Friberg, A, Puetter, V, Nguyen, D, Rehwinkel, H. 登録日 2019-07-22 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A. Acs Omega, 5, 2020
6SBV	X-ray Structure of Human LDH-A with an Allosteric Inhibitor (Compound 7) 分子名称: L-lactate dehydrogenase A chain, ~{N}-[3-[(7-nitrodibenzofuran-2-yl)sulfonylamino]phenyl]-1-oxidanyl-cyclopropane-1-carboxamide 著者 Friberg, A, Puetter, V, Nguyen, D, Rehwinkel, H. 登録日 2019-07-22 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A. Acs Omega, 5, 2020

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