PDB: 194 件ウェブページステータス検索Chemie searchBIRD

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3ORR	Crystal Structure of N5-Carboxyaminoimidazole synthetase from Staphylococcus aureus 分子名称: N5-carboxyaminoimidazole ribonucleotide synthetase 著者 Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. 登録日 2010-09-07 公開日 2011-07-20 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
7VA1	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35 分子名称: 4-[(3-ethanoylphenyl)sulfamoyl]-~{N}-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]benzamide, D-3-phosphoglycerate dehydrogenase 著者 Cen, Y, Gao, D, Zhou, J, Tian, P. 登録日 2021-08-27 公開日 2023-03-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35 To Be Published
3ORQ	Crystal Structure of N5-Carboxyaminoimidazole synthetase from Staphylococcus aureus complexed with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. 登録日 2010-09-07 公開日 2011-07-20 最終更新日 2012-03-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
7WN9	Dictyostelium discoideum Lactate dehydrogenase (DicLDHA) 分子名称: ACETATE ION, Putative D-lactate dehydrogenase 著者 Dao, O, Lee, K.H. 登録日 2022-01-17 公開日 2022-04-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dictyostelium discoideum Lactate dehydrogenase (DicLDHA) To Be Published
5N53	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with N-(3-chloro-4-methoxyphenyl) acetamide 分子名称: D-3-phosphoglycerate dehydrogenase, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide 著者 Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. 登録日 2017-02-12 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
7YA4	Formate dehydrogenase from Novosphingobium sp. AP12 with NAD and Azide 分子名称: 1,2-ETHANEDIOL, ACETATE ION, AZIDE ION, ... 著者 Kim, S, Kim, K.-J. 登録日 2022-06-27 公開日 2023-07-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dual cofactor specific formate dehydrogenase from Novosphingobium sp. AP12 with high activity. To Be Published
7YA3	Formate dehydrogenase from Novosphingobium sp. AP12 with NADP and Azide 分子名称: AZIDE ION, Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Kim, S, Kim, K.-J. 登録日 2022-06-27 公開日 2023-07-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Dual cofactor specific formate dehydrogenase from Novosphingobium sp. AP12 with high activity. To Be Published
6CDF	Human CtBP1 (28-378) 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, CALCIUM ION, ... 著者 Royer, W.E, Bellesis, A.G. 登録日 2018-02-08 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
2WWR	Crystal Structure of Human Glyoxylate Reductase Hydroxypyruvate Reductase 分子名称: GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE, MAGNESIUM ION 著者 Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. 登録日 2009-10-26 公開日 2010-10-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase. J.Mol.Biol., 360, 2006
6CDR	Human CtBP1 (28-378) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, ... 著者 Royer, W.E, Bellesis, A.G. 登録日 2018-02-09 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
6CWA	CRYSTAL STRUCTURE PHGDH IN COMPLEX WITH NADH AND 3-PHOSPHOGLYCERATE AT 1.77 A RESOLUTION 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-PHOSPHOGLYCERIC ACID, D-3-phosphoglycerate dehydrogenase 著者 Davies, D.R, Edwards, T.E. 登録日 2018-03-30 公開日 2019-08-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis. J.Med.Chem., 62, 2019
6D4B	Crystal structure of Candida boidinii formate dehydrogenase V123A mutant complexed with NAD+ and azide 分子名称: AZIDE ION, CHLORIDE ION, Formate dehydrogenase, ... 著者 Guo, Q, Ye, H, Gakhar, L, Cheatum, C.M, Kohen, A. 登録日 2018-04-17 公開日 2019-04-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase Acs Catalysis, 2019
6D4C	Crystal structure of Candida boidinii formate dehydrogenase V123G mutant complexed with NAD+ and azide 分子名称: AZIDE ION, CHLORIDE ION, Formate dehydrogenase, ... 著者 Guo, Q, Ye, H, Gakhar, L, Cheatum, C.M, Kohen, A. 登録日 2018-04-17 公開日 2019-04-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase Acs Catalysis, 2019
2YQ4	Crystal Structure of D-isomer specific 2-hydroxyacid dehydrogenase from Lactobacillus delbrueckii ssp. bulgaricus 分子名称: D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE 著者 Holton, S.J, Anandhakrishnan, M, Geerlof, A, Wilmanns, M. 登録日 2012-11-05 公開日 2012-11-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural Characterization of D-Isomer Specific 2-Hydroxyacid Dehydrogenase from Lactobacillus Delbrueckii Ssp. Bulgaricus J.Struct.Biol., 181, 2013
1GDH	CRYSTAL STRUCTURE OF A NAD-DEPENDENT D-GLYCERATE DEHYDROGENASE AT 2.4 ANGSTROMS RESOLUTION 分子名称: D-GLYCERATE DEHYDROGENASE, SULFATE ION 著者 Goldberg, J.D, Yoshida, T, Brick, P. 登録日 1993-09-22 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution. J.Mol.Biol., 236, 1994
2YQ5	Crystal Structure of D-isomer specific 2-hydroxyacid dehydrogenase from Lactobacillus delbrueckii ssp. bulgaricus: NAD complexed form 分子名称: D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Holton, S.J, Anandhakrishnan, M, Geerlof, A, Wilmanns, M. 登録日 2012-11-05 公開日 2012-11-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural Characterization of D-Isomer Specific 2-Hydroxyacid Dehydrogenase from Lactobacillus Delbrueckii Ssp. Bulgaricus J.Struct.Biol., 181, 2013
1HKU	CtBP/BARS: a dual-function protein involved in transcription corepression and Golgi membrane fission 分子名称: C-TERMINAL BINDING PROTEIN 3, FORMIC ACID, GLYCEROL, ... 著者 Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. 登録日 2003-03-11 公開日 2003-06-19 最終更新日 2016-12-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission Embo J., 22, 2003
1HL3	CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide 分子名称: C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE 著者 Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. 登録日 2003-03-13 公開日 2003-06-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission Embo J., 22, 2003
1J4A	INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS 分子名称: D-LACTATE DEHYDROGENASE, SULFATE ION 著者 Razeto, A, Kochhar, S, Hottinger, H, Dauter, M, Wilson, K.S, Lamzin, V.S. 登録日 2001-08-18 公開日 2002-05-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus. J.Mol.Biol., 318, 2002
1J49	INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS 分子名称: D-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Razeto, A, Kochhar, S, Hottinger, H, Dauter, M, Wilson, K.S, Lamzin, V.S. 登録日 2001-08-14 公開日 2002-05-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus. J.Mol.Biol., 318, 2002
3BAZ	Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 分子名称: Hydroxyphenylpyruvate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Janiak, V, Klebe, G, Petersen, M, Heine, A. 登録日 2007-11-09 公開日 2008-11-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth Acta Crystallogr.,Sect.D, 66, 2010
3BA1	Structure of hydroxyphenylpyruvate reductase from coleus blumei 分子名称: Hydroxyphenylpyruvate reductase 著者 Janiak, V, Klebe, G, Petersen, M, Heine, A. 登録日 2007-11-07 公開日 2008-11-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth. Acta Crystallogr.,Sect.D, 66, 2010
2HU2	CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide 分子名称: 9-mer peptide from Zinc finger protein 217, C-terminal-binding protein 1, FORMIC ACID, ... 著者 Nardini, M, Bolognesi, M, Quinlan, K.G.R, Verger, A, Francescato, P, Crossley, M. 登録日 2006-07-26 公開日 2006-10-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins Mol.Cell.Biol., 26, 2006
2J6I	Candida boidinii formate dehydrogenase (FDH) C-terminal mutant 分子名称: FORMATE DEHYDROGENASE, TETRAETHYLENE GLYCOL 著者 Schirwitz, K, Schmidt, A, Lamzin, V.S. 登録日 2006-09-29 公開日 2007-06-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High-Resolution Structures of Formate Dehydrogenase from Candida Boidinii. Protein Sci., 16, 2007
7DKM	PHGDH covalently linked to oridonin 分子名称: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, CHLORIDE ION, D-3-phosphoglycerate dehydrogenase, ... 著者 Sun, Q, Lei, Y. 登録日 2020-11-25 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors. Cell.Mol.Life Sci., 79, 2021

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