PDB: 125 resultsInfo pagesStatus searchChemie searchBIRD

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6AMS	Crystal structure of the DNA polymerase III subunit beta from Pseudomonas aeruginosa Descriptor: Beta sliding clamp, PHOSPHATE ION Authors: McGrath, A.E, Oakley, A.J. Deposit date: 2017-08-11 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
6AMQ	Crystal structure of the DNA polymerase III subunit beta from Enterobacter cloacae Descriptor: DNA polymerase III subunit beta, SULFATE ION Authors: McGrath, A.E, Oakley, A.J. Deposit date: 2017-08-11 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
8VAS	Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAT	Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAM	Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAP	Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
5FKU	cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA polymerase III alpha, beta, epsilon, tau complex) Descriptor: DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ... Authors: Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. Deposit date: 2015-10-20 Release date: 2015-11-25 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (8.34 Å) Cite: cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
5FRQ	Crystal Structure of Helicobacter pylori beta clamp bound to DNA ligase peptide Descriptor: DNA LIGASE, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2015-12-21 Release date: 2016-08-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Insight Into Beta-Clamp and its Interaction with DNA Ligase in Helicobacter Pylori Sci.Rep., 6, 2016
5FKW	cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon) Descriptor: DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ... Authors: Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. Deposit date: 2015-10-20 Release date: 2015-11-25 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (7.3 Å) Cite: cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
5FXT	Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-03-02 Release date: 2017-08-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
3P16	Crystal structure of DNA polymerase III sliding clamp Descriptor: DNA polymerase III subunit beta Authors: Gui, W.J, Lin, S.Q, Chen, Y.Y, Zhang, X.E, Bi, L.J, Jiang, T. Deposit date: 2010-09-30 Release date: 2011-08-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis. Biochem.Biophys.Res.Commun., 405, 2011
5FKV	cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex) Descriptor: DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ... Authors: Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. Deposit date: 2015-10-20 Release date: 2015-11-25 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (8.04 Å) Cite: cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
5FVE	Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide Descriptor: 3,4-difluorobenzamide, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-02-05 Release date: 2017-02-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
3Q4J	Structure of a small peptide ligand bound to E.coli DNA sliding clamp Descriptor: DNA polymerase III subunit beta, peptide ligand Authors: Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. Deposit date: 2010-12-23 Release date: 2011-12-28 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011
5G4Q	H.pylori Beta clamp in complex with 5-chloroisatin Descriptor: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-05-16 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
5G48	H.pylori Beta clamp in complex with Diflunisal Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-05-06 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
3Q4K	Structure of a small peptide ligand bound to E.coli DNA sliding clamp Descriptor: DNA polymerase III subunit beta, peptide ligand Authors: Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. Deposit date: 2010-12-23 Release date: 2011-12-28 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011
3Q4L	Structure of a small peptide ligand bound to E.coli DNA sliding clamp Descriptor: DNA polymerase III subunit beta, SODIUM ION, peptide ligand Authors: Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. Deposit date: 2010-12-23 Release date: 2011-12-28 Last modified: 2013-03-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011
3PWE	Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution Descriptor: DNA polymerase III subunit beta Authors: Marzahn, M.R, Robbins, A.H, McKenna, R, Bloom, L.B. Deposit date: 2010-12-08 Release date: 2011-10-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.199 Å) Cite: The E. coli clamp loader can actively pry open the beta-sliding clamp J.Biol.Chem., 286, 2011
3QSB	Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile Descriptor: (1R,5R)-5-{(1Z)-N-[(4'-fluorobiphenyl-4-yl)methoxy]butanimidoyl}-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile, DNA polymerase III subunit beta Authors: Wijffels, G, Johnson, W.M, Oakley, A.J, Turner, K, Epa, V.C, Briscoe, S.J, Polley, M, Liepa, A.J, Hofmann, A, Buchardt, J, Christensen, C, Prosselkov, P, Dalrymple, B.P, Alewood, P.F, Jennings, P.A, Dixon, N.E, Winkler, D.A. Deposit date: 2011-02-20 Release date: 2011-06-08 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Binding inhibitors of the bacterial sliding clamp by design J.Med.Chem., 54, 2011
3RB9	Crystal structure of the M. tuberculosis beta clamp Descriptor: DNA polymerase III subunit beta Authors: Kukshal, V, Ramachandran, R. Deposit date: 2011-03-29 Release date: 2012-04-04 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3 Å) Cite: M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase Plos One, 7, 2012
3T0P	Crystal structure of a Putative DNA polymerase III beta subunit (EUBREC_0002; ERE_29750) from Eubacterium rectale ATCC 33656 at 2.26 A resolution Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2011-07-20 Release date: 2011-08-10 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Crystal structure of a Putative DNA polymerase III beta subunit (EUBREC_0002; ERE_29750) from Eubacterium rectale ATCC 33656 at 2.26 A resolution To be published

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