8PF8
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-72 | 分子名称: | (2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2023-06-15 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
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8OQO
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8OQT
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8OQL
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8OQQ
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8OQS
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8OQR
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8OQV
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8OQN
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8OQP
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8OQM
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8OQU
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8OPX
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8OPU
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8OPW
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8OPY
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-B-DNQ | 分子名称: | 3-hydroxyacyl-CoA dehydrogenase, 6,7-DINITROQUINOXALINE-2,3-DIONE, GLYCEROL, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2023-04-10 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
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8OPV
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8BRJ
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | 登録日 | 2022-11-23 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BNU
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | 登録日 | 2022-11-14 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BNR
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | 登録日 | 2022-11-14 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (10.3 Å) | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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7O4V
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide | 分子名称: | 3-hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative acyltransferase Rv0859, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2021-04-07 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O4U
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7O4Q
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in space group C2221 (unliganded) | 分子名称: | 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2021-04-07 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O4R
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the thiolase active sites and additional binding site (CoA(HAD/KAT)) | 分子名称: | 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2021-04-07 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O4T
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the hydratase, thiolase active sites and possible additional binding site (CoA(ECH/HAD)) | 分子名称: | 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, ... | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | 登録日 | 2021-04-07 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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