PDB: 92 件ウェブページステータス検索Chemie searchBIRD

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1D1Q	CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE SUBSTRATE PNPP 分子名称: 4-NITROPHENYL PHOSPHATE, GLYCEROL, PHOSPHATE ION, ... 著者 Wang, S, Tabernero, L, Zhang, M, Harms, E, Van Etten, R.L, Staufacher, C.V. 登録日 1999-09-20 公開日 2000-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate. Biochemistry, 39, 2000
7DHD	Vibrio vulnificus Wzb 分子名称: CHLORIDE ION, Protein-tyrosine-phosphatase 著者 Ma, Q, Wang, X. 登録日 2020-11-14 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
3RH0	Corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate reductase Cg_ArsC2 分子名称: ARSENATE REDUCTASE 著者 Messens, J, Wahni, K, Dufe, T.V. 登録日 2011-04-11 公開日 2011-11-30 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.724 Å) 主引用文献 Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms Mol.Microbiol., 82, 2011
6Y2W	Crystal structure of the single mutant I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) 分子名称: ACETATE ION, Low molecular weight phosphotyrosine protein phosphatase 著者 Levy, C. 登録日 2020-02-17 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme. Plos One, 15, 2020
3JVI	Product state mimic crystal structure of protein tyrosine phosphatase from Entamoeba histolytica 分子名称: Protein tyrosine phosphatase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-16 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193, 2014
4KK4	YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
4ETI	Crystal Structure of YwlE from Bacillus subtilis 分子名称: FORMIC ACID, Low molecular weight protein-tyrosine-phosphatase ywlE 著者 Cao, X.F, Brostromer, E, Liu, X.Y, Su, X.D. 登録日 2012-04-24 公開日 2012-05-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of YwlE from Bacillus subtilis TO BE PUBLISHED
2FXI	Arsenate reductase (ArsC from pI258) C10S/C15A double mutant with sulfate in its active site 分子名称: POTASSIUM ION, Protein arsC, SULFATE ION 著者 Loris, R, Buts, L, Messens, J. 登録日 2006-02-06 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Interplay Between Ion Binding and Catalysis in the Thioredoxin-coupled Arsenate Reductase Family. J.Mol.Biol., 360, 2006
5JNS	Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate 分子名称: DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION 著者 Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. 登録日 2016-04-30 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
5JNW	Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with vanadate and uncompetitive inhibitor 分子名称: 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile, Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION 著者 Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. 登録日 2016-04-30 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
2CWD	Crystal Structure of TT1001 protein from Thermus thermophilus HB8 分子名称: MAGNESIUM ION, low molecular weight phosphotyrosine protein phosphatase 著者 Lokanath, N.K, Terao, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-06-20 公開日 2006-09-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of TT1001 protein from Thermus thermophilus HB8 To be Published
1D2A	CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE ACTIVATOR ADENINE 分子名称: ADENINE, CHLORIDE ION, PHOSPHATE ION, ... 著者 Wang, S, Stauffacher, C.V, Van Etten, R.L. 登録日 1999-09-22 公開日 2000-03-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and mechanistic basis for the activation of a low-molecular weight protein tyrosine phosphatase by adenine. Biochemistry, 39, 2000
1DG9	CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PTPASE COMPLEXED WITH HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TYROSINE PHOSPHATASE 著者 Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. 登録日 1999-11-23 公開日 1999-12-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of bovine low molecular weight phosphotyrosyl phosphatase complexed with the transition state analog vanadate. Biochemistry, 36, 1997
1U2P	Crystal structure of Mycobacterium tuberculosis Low Molecular Protein Tyrosine Phosphatase (MPtpA) at 1.9A resolution 分子名称: CHLORIDE ION, low molecular weight protein-tyrosine-phosphatase 著者 Madhurantakam, C, Rajakumara, E, Mazumdar, P.A, Saha, B, Mitra, D, Wiker, H.G, Sankaranarayanan, R, Das, A.K. 登録日 2004-07-20 公開日 2005-03-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Low-Molecular-Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis at 1.9-A Resolution J.Bacteriol., 187, 2005
2P4U	Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus 分子名称: Acid phosphatase 1, PHOSPHATE ION 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-03-13 公開日 2007-03-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
5GOT	Crystal structure of SP-PTP, low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes 分子名称: CHLORIDE ION, Low molecular weight phosphotyrosine phosphatase family protein 著者 Ku, B, Keum, C.W, KIim, S.J. 登録日 2016-07-29 公開日 2016-09-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes Biochem.Biophys.Res.Commun., 478, 2016
5KQM	Co-crystal structure of LMW-PTP in complex with MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.-Y, Yu, Z.-H. 登録日 2016-07-06 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016
3JS5	Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with Hepes in the active site. High resolution, alternative crystal form with 1 molecule in asymmetric unit 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-09 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193, 2014
5JNR	Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A 分子名称: Low molecular weight phosphotyrosine protein phosphatase 著者 Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. 登録日 2016-04-30 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
6Y2V	Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) 分子名称: Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, TRIETHYLENE GLYCOL 著者 Levy, C. 登録日 2020-02-17 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme. Plos One, 15, 2020
1JFV	X-Ray Structure of oxidised C10S, C15A arsenate reductase from pI258 分子名称: PERCHLORATE ION, POTASSIUM ION, arsenate reductase 著者 Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. 登録日 2001-06-22 公開日 2001-10-03 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Nat.Struct.Biol., 8, 2001
1LJL	Wild Type pI258 S. aureus arsenate reductase 分子名称: POTASSIUM ION, arsenate reductase 著者 Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. 登録日 2002-04-21 公開日 2002-08-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
5KQP	Crystal structure of Apo-form LMW-PTP 分子名称: Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.-Y, Yu, Z.-H. 登録日 2016-07-06 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016
7CUY	Crystal structure of Primo-1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase 1 著者 Lee, H.S, Kim, S.J, Ku, B. 登録日 2020-08-25 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.081 Å) 主引用文献 Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1. Mol.Cells, 43, 2020
4Z9A	Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with phenylmethanesulfonic acid 分子名称: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION, ... 著者 Trivella, D.B.B, Fonseca, E.M.B, Scorsato, V, Dias, M.P, Aparicio, R. 登録日 2015-04-10 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23, 2015

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