6G8B
 
 | | E. coli Aminopeptidase N solved by Native SAD from a dataset collected in 60 second with JUNGFRAU detector | | 分子名称: | Aminopeptidase N, DIMETHYL SULFOXIDE, SODIUM ION, ... | | 著者 | Leonarski, F, Olieric, V, Redford, S, Wang, M. | | 登録日 | 2018-04-08 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.374 Å) | | 主引用文献 | Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector.
Nat. Methods, 15, 2018
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5Y3I
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5ZI7
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5ZI5
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5ZIE
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5YO1
 | | Structure of ePepN E298A mutant in complex with Puromycin | | 分子名称: | Aminopeptidase N, GLYCEROL, PUROMYCIN, ... | | 著者 | Ganji, R.J, Reddi, R, Marapaka, A.K, Addlagatta, A. | | 登録日 | 2017-10-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
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5YQ1
 | | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine | | 分子名称: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine
To Be Published
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5YQ2
 | | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside | | 分子名称: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside
To Be Published
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5YQB
 | | Crystal structure of E.coli aminopeptidase N in complex with Puromycin | | 分子名称: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
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6EE3
 | | X-ray crystal structure of Pf-M1 in complex with inhibitor (6k) and catalytic zinc ion | | 分子名称: | (1R,2r,3S,5R,7R)-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]tricyclo[3.3.1.1~3,7~]decane-2-carboxamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Drinkwater, N, McGowan, S. | | 登録日 | 2018-08-13 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
J. Med. Chem., 62, 2019
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6EED
 | | X-ray crystal structure of Pf-M1 in complex with inhibitor (6p) and catalytic zinc ion | | 分子名称: | (2R)-2-[(cyclohexylacetyl)amino]-N-hydroxy-2-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)acetamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Drinkwater, N, McGowan, S. | | 登録日 | 2018-08-13 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
J. Med. Chem., 62, 2019
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6EA2
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6EAB
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6EAA
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6EA1
 | | X-ray crystal structure of Pf-M1 in complex with inhibitor (6da) and catalytic zinc ion | | 分子名称: | (2R)-2,3,3,3-tetrafluoro-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]propanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Drinkwater, N, McGowan, S. | | 登録日 | 2018-08-02 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.815 Å) | | 主引用文献 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
J. Med. Chem., 62, 2019
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6EE4
 | | X-ray crystal structure of Pf-M1 in complex with inhibitor (6m) and catalytic zinc ion | | 分子名称: | (2R)-2-[(cyclopropylacetyl)amino]-N-hydroxy-2-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)acetamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Drinkwater, N, McGowan, S. | | 登録日 | 2018-08-13 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
J. Med. Chem., 62, 2019
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6EE6
 | | X-ray crystal structure of Pf-M1 in complex with inhibitor (6o) and catalytic zinc ion | | 分子名称: | (2R)-2-[(cyclopentylacetyl)amino]-N-hydroxy-2-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)acetamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Drinkwater, N, McGowan, S. | | 登録日 | 2018-08-13 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
J. Med. Chem., 62, 2019
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5Z65
 | | Crystal structure of porcine aminopeptidase N ectodomain in functional form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sun, Y.G, Li, R, Jiang, L.G, Qiao, S.L, Zhang, G.P. | | 登録日 | 2018-01-22 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Characterization of the interaction between recombinant porcine aminopeptidase N and spike glycoprotein of porcine epidemic diarrhea virus.
Int. J. Biol. Macromol., 117, 2018
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6Q4R
 | | High-resolution crystal structure of ERAP1 with bound phosphinic transition-state analogue inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Giastas, P, Neu, M, Rowland, P, Stratikos, E. | | 登録日 | 2018-12-06 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-Resolution Crystal Structure of Endoplasmic Reticulum Aminopeptidase 1 with Bound Phosphinic Transition-State Analogue Inhibitor.
Acs Med.Chem.Lett., 10, 2019
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6A8Z
 | | Crystal structure of M1 zinc metallopeptidase from Deinococcus radiodurans | | 分子名称: | SODIUM ION, TYROSINE, ZINC ION, ... | | 著者 | Agrawal, R, Kumar, A, Makde, R.D. | | 登録日 | 2018-07-11 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.045 Å) | | 主引用文献 | Two-domain aminopeptidase of M1 family: Structural features for substrate binding and gating in absence of C-terminal domain.
J.Struct.Biol., 208, 2019
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6IFG
 | | Crystal structure of M1 zinc metallopeptidase E323A mutant bound to Tyr-ser-ala substrate from Deinococcus radiodurans | | 分子名称: | FORMIC ACID, Tripeptides (TYR-SER-ALA), ZINC ION, ... | | 著者 | Agrawal, R, Kumar, A, Kumar, A, Makde, R.D. | | 登録日 | 2018-09-20 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Two-domain aminopeptidase of M1 family: Structural features for substrate binding and gating in absence of C-terminal domain.
J.Struct.Biol., 208, 2019
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6IFF
 | | Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans | | 分子名称: | SODIUM ION, TYROSINE, ZINC ION, ... | | 著者 | Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D. | | 登録日 | 2018-09-20 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
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6U7E
 | | HCoV-229E RBD Class III in complex with human APN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Tomlinson, A.C.A, Li, Z, Rini, J.M. | | 登録日 | 2019-09-02 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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6U7G
 | | HCoV-229E RBD Class V in complex with human APN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Tomlinson, A, Li, Z, Rini, J.M. | | 登録日 | 2019-09-02 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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6U7F
 | | HCoV-229E RBD Class IV in complex with human APN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Tomlinson, A.C.A, Li, Z, Rini, J.M. | | 登録日 | 2019-09-02 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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