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3NVQ
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Molecular mechanism of guidance cue recognition
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, ...
著者Juo, Z, Liu, H, Shim, A, Focia, P, Chen, X, Garcia, C, He, X.
登録日2010-07-08
公開日2010-09-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
3OKT
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Mouse Plexin A2, extracellular domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y.
登録日2010-08-25
公開日2010-10-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
3OKW
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Mouse Semaphorin 6A, extracellular domains 1-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
著者Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y.
登録日2010-08-25
公開日2010-10-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
3OKY
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Plexin A2 in complex with Semaphorin 6A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y.
登録日2010-08-25
公開日2010-10-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
7Y4Q
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Semaphorin 6D in complex with Plexin A1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, ...
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-16
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
7Y4O
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BU of 7y4o by Molmil
Rat Semaphorin 6D extracellular region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin 6D
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
7Y4P
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Human Plexin A1, extracellular domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
5L5N
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Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 angstrom, spacegroup P4(3)22
分子名称: Plexin-A4
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (8.502 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L5G
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Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom
分子名称: Plexin-A2
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (10 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L5M
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Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8 angstrom, spacegroup P4(3)2(1)2
分子名称: Plexin-A4
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (8 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L59
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Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P2(1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L5K
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BU of 5l5k by Molmil
Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)
分子名称: Plexin-A4
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (7.501 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L5L
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BU of 5l5l by Molmil
Plexin A4 full extracellular region, domains 1 to 8 modeled, data to 8 angstrom, spacegroup P2(1)
分子名称: Plexin-A4
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (8.001 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L56
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BU of 5l56 by Molmil
Plexin A1 full extracellular region, domains 1 to 10, to 4 angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
5L5C
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BU of 5l5c by Molmil
Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P4(3)2(1)2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, ...
著者Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y.
登録日2016-05-28
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
4K3J
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BU of 4k3j by Molmil
Crystal structure of Onartuzumab Fab in complex with MET and HGF-beta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor beta chain, ...
著者Ma, X, Starovasnik, M.A.
登録日2013-04-10
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Proc.Natl.Acad.Sci.USA, 110, 2013
1OLZ
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BU of 1olz by Molmil
The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D
分子名称: SEMAPHORIN 4D
著者Love, C.A, Harlos, K, Mavaddat, N, Davis, S.J, Stuart, D.I, Jones, E.Y, Esnouf, R.M.
登録日2003-08-19
公開日2003-09-11
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Ligand-Binding Face of the Semaphorins Revealed by the High-Resolution Crystal Structure of Sema4D
Nat.Struct.Biol., 10, 2003
1SHY
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BU of 1shy by Molmil
The Crystal Structure of HGF beta-chain in Complex with the Sema Domain of the Met Receptor.
分子名称: Hepatocyte growth factor, Hepatocyte growth factor receptor
著者Stamos, J, Wiesmann, C.
登録日2004-02-26
公開日2004-06-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor.
Embo J., 23, 2004
4O3U
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BU of 4o3u by Molmil
Zymogen HGF-beta/MET with Zymogen Activator Peptide ZAP2.3
分子名称: Hepatocyte growth factor, Hepatocyte growth factor receptor, ZAP 2.3
著者Eigenbrot, C, Landgraf, K.E, Steffek, M.
登録日2013-12-18
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.
Nat.Chem.Biol., 10, 2014
4O3T
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BU of 4o3t by Molmil
Zymogen HGF-beta/MET with Zymogen Activator Peptide ZAP.14
分子名称: Hepatocyte growth factor, Hepatocyte growth factor receptor, PENTAETHYLENE GLYCOL, ...
著者Eigenbrot, C, Landgraf, K.E, Steffek, M.
登録日2013-12-18
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.
Nat.Chem.Biol., 10, 2014
4QT8
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BU of 4qt8 by Molmil
Crystal Structure of RON Sema-PSI-IPT1 extracellular domains in complex with MSP beta-chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hepatocyte growth factor-like protein, Macrophage-stimulating protein receptor, ...
著者Herzberg, O, Chao, K.L.
登録日2014-07-07
公開日2014-09-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the binding specificity of human Recepteur d'Origine Nantais (RON) receptor tyrosine kinase to macrophage-stimulating protein.
J.Biol.Chem., 289, 2014
4GZA
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BU of 4gza by Molmil
Complex of mouse Plexin A2 - Semaphorin 3A - Neuropilin-1
分子名称: CALCIUM ION, Neuropilin-1, Plexin-A2, ...
著者Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y.
登録日2012-09-06
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
Nat.Struct.Mol.Biol., 19, 2012
3OL2
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BU of 3ol2 by Molmil
Receptor-ligand structure of Human Semaphorin 4D with Plexin B1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, ...
著者Janssen, B.J.C, Robinson, R.A, Perez-Branguli, F, Bell, C.H, Mitchell, C.J, Siebold, C, Jones, E.Y.
登録日2010-08-25
公開日2010-10-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
7VG7
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BU of 7vg7 by Molmil
Plexin B1 extracellular fragment in complex with lasso-grafted PB1m6A9 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, TRIETHYLENE GLYCOL, ...
著者Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J.
登録日2021-09-14
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Structure, 30, 2022
7VF3
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BU of 7vf3 by Molmil
Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ...
著者Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J.
登録日2021-09-10
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Structure, 30, 2022

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