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7V49
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BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4C
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BU of 7v4c by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 4
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 4
To Be Published
7V4B
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BU of 7v4b by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 3
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 3
To Be Published
7V48
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BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4A
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BU of 7v4a by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 1
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 1
To Be Published
7V4D
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BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-remodelled alpha-synuclein fibrils
To Be Published
7WMM
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BU of 7wmm by Molmil
alpha-synuclein fibril-F0502B complex
Descriptor: 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-01-15
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:alpha-synuclein fibril-F0502B complex
To Be Published
7WO0
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BU of 7wo0 by Molmil
CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions
Descriptor: Alpha-synuclein
Authors:Wu, K.-P, Huang, J.Y.-C.
Deposit date:2022-01-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation
To Be Published
7WNZ
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BU of 7wnz by Molmil
CryoEM structure of human alpha-synuclein A53T fibril
Descriptor: Alpha-synuclein
Authors:Wu, K.-P, Huang, J.Y.-C.
Deposit date:2022-01-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation
To Be Published
7XO2
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BU of 7xo2 by Molmil
Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO3
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BU of 7xo3 by Molmil
Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO0
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BU of 7xo0 by Molmil
Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO1
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BU of 7xo1 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XJX
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BU of 7xjx by Molmil
The cryo-EM structure of Fe3+ induced alpha-syn fibril.
Descriptor: Alpha-synuclein
Authors:Zhao, Q.Y, Tao, Y.Q, Zhao, K, Tao, Y.Q, Li, D.
Deposit date:2022-04-18
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural Insights of Fe3+ Induced alpha-synuclein Fibrillation in Parkinson' Disease
J.Mol.Biol., 435, 2023
7YNT
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BU of 7ynt by Molmil
pFTAA-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:pFTAA-bound alpha-synuclein fibrils
To Be Published
7YNG
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BU of 7yng by Molmil
CR-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-30
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:CR-bound alpha-synuclein fibrils
To Be Published
7YNQ
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BU of 7ynq by Molmil
PiB-bound alpha-synuclein fibrils conformation 2
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:PiB-bound alpha-synuclein fibrils conformation 2
To Be Published
7YNS
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BU of 7yns by Molmil
SIL5-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SIL5-bound alpha-synuclein fibrils
To Be Published
7YK2
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BU of 7yk2 by Molmil
Cryo-EM structure of Apo-alpha-syn fibril
Descriptor: Alpha-synuclein
Authors:Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
Deposit date:2022-07-21
Release date:2023-03-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YK8
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BU of 7yk8 by Molmil
Cryo-EM structure of dLAG3-alpha-syn fibril
Descriptor: Alpha-synuclein
Authors:Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
Deposit date:2022-07-22
Release date:2023-03-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YNR
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BU of 7ynr by Molmil
C05-03-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:C05-03-bound alpha-synuclein fibrils
To Be Published
7YNP
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BU of 7ynp by Molmil
BF227-bound alpha-synuclein fibrils
Descriptor: 5-[(~{E})-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]-~{N},~{N}-dimethyl-1,3-thiazol-2-amine, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:BF227-bound alpha-synuclein fibrils
To Be Published
7YNN
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BU of 7ynn by Molmil
ThT-bound alpha-synuclein fibrils conformation 2
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:ThT-bound alpha-synuclein fibrils conformation 2
To Be Published
7YNO
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BU of 7yno by Molmil
PiB-bound alpha-synuclein fibrils conformation 1
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:PiB-bound alpha-synuclein fibrils conformation 1
To Be Published
7YNL
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BU of 7ynl by Molmil
EB-bound alpha-synuclein fibrils
Descriptor: 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:EB-bound alpha-synuclein fibrils
To Be Published

219869

數據於2024-05-15公開中

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