PDB: 40 resultsInfo pagesStatus searchChemie searchBIRD

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7WK7	Mouse Pendrin bound bicarbonate in inward state Descriptor: BICARBONATE ION, Pendrin Authors: Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. Deposit date: 2022-01-08 Release date: 2023-05-17 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
8OPQ	Structure of Human Solute Carrier 26 family member A6 (SLC26A6) anion transporter in an inward-facing state Descriptor: CHLORIDE ION, Solute carrier family 26 member 6 Authors: Tippett, D.N, Breen, C, Butler, S.J, Sawicka, M, Dutzler, R. Deposit date: 2023-04-07 Release date: 2023-05-17 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange. Elife, 12, 2023
7XUJ	Human SLC26A3 in complex with UK5099 Descriptor: (E)-2-cyano-3-(1-phenylindol-3-yl)prop-2-enoic acid, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger Authors: Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. Deposit date: 2022-05-18 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: human SLC26A3 in complex with UK5099 To Be Published
7XUL	Human SLC26A3 in complex with Tenidap Descriptor: 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger Authors: Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. Deposit date: 2022-05-18 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structure of human SLC26A3 in complex with Tenidap To Be Published
7XUH	Down-regulated in adenoma in complex with TQR1122 Descriptor: 2-[4,8-dimethyl-2-oxidanylidene-7-[[3-(trifluoromethyl)phenyl]methoxy]chromen-3-yl]ethanoic acid, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger Authors: Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. Deposit date: 2022-05-18 Release date: 2023-08-02 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: structure of human SLC26A3 in complex with TQR1122 To Be Published
7WLB	Mouse Pendrin in chloride and iodide buffer in asymmetric state Descriptor: Pendrin Authors: Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. Deposit date: 2022-01-12 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
7WL8	Mouse Pendrin in chloride and iodide buffer in inward state Descriptor: Pendrin Authors: Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. Deposit date: 2022-01-12 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
8UC1	Cryo-EM structure of dolphin Prestin in low Cl buffer Descriptor: CHLORIDE ION, Prestin Authors: Haller, P, Bavi, N, Perozo, E. Deposit date: 2023-09-25 Release date: 2023-12-13 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility. Elife, 12, 2023
8HZN	Mouse Pendrin bound chloride in inward state Descriptor: CHLORIDE ION, Pendrin Authors: Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. Deposit date: 2023-01-09 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Mouse Pendrin bound chloride in inward state To Be Published
8UUK	Pendrin in apo Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... Authors: Wang, L, Hoang, A, Zhou, M. Deposit date: 2023-11-01 Release date: 2024-02-07 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8SHC	Pendrin in complex with Niflumic acid Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... Authors: Wang, L, Hoang, A, Zhou, M. Deposit date: 2023-04-13 Release date: 2024-02-07 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8SH3	Pendrin in complex with iodide Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, IODIDE ION, ... Authors: Wang, L, Hoang, A, Zhou, M. Deposit date: 2023-04-13 Release date: 2024-02-07 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8SIE	Pendrin in complex with bicarbonate Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, BICARBONATE ION, CHOLESTEROL, ... Authors: Wang, L, Hoang, A, Zhou, M. Deposit date: 2023-04-16 Release date: 2024-02-07 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8SGW	Pendrin in complex with chloride Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... Authors: Wang, L, Hoang, A, Zhou, M. Deposit date: 2023-04-13 Release date: 2024-02-07 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8IET	Human SLC26A3 in the apo state Descriptor: Chloride anion exchanger Authors: Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. Deposit date: 2023-02-15 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Human SLC26A3 in the apo state To Be Published

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