PDB: 27 resultsInfo pagesStatus searchChemie searchBIRD

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6VGD

Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC Descriptor: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... Authors: Hou, C, Tsodikov, O.V. Deposit date: 2020-01-07 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021

6VGG

Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC Descriptor: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... Authors: Hou, C, Rohr, J, Tsodikov, O.V. Deposit date: 2020-01-08 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.31 Å) Cite: Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021

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