2G6Z
| Crystal structure of human DUSP5 | Descriptor: | Dual specificity protein phosphatase 5, SULFATE ION | Authors: | Kim, S.J, Ryu, S.E. | Deposit date: | 2006-02-26 | Release date: | 2007-01-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase Proteins, 66, 2007
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2GWO
| crystal structure of TMDP | Descriptor: | Dual specificity protein phosphatase 13 | Authors: | Kim, S.J, Ryu, S.E, Kim, J.H. | Deposit date: | 2006-05-05 | Release date: | 2007-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity Proteins, 66, 2007
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2HCM
| Crystal structure of mouse putative dual specificity phosphatase complexed with zinc tungstate, New York Structural Genomics Consortium | Descriptor: | Dual specificity protein phosphatase, GLYCEROL, SODIUM ION, ... | Authors: | Patskovsky, Y, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-06-17 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
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4HRF
| Atomic structure of DUSP26 | Descriptor: | Dual specificity protein phosphatase 26 | Authors: | Lokareddy, R.K, Bhardwaj, A, Cingolani, G. | Deposit date: | 2012-10-27 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase. Biochemistry, 52, 2013
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7UN4
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | Descriptor: | 1-{[(9aM)-5,6-dihydrothieno[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10 | Authors: | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | Deposit date: | 2022-04-08 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
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7UN0
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-chloro-5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | Descriptor: | 1-[(9-chlorobenzo[h]quinazolin-2-yl)sulfanyl]-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10 | Authors: | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | Deposit date: | 2022-04-08 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
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7UMU
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | Descriptor: | 1-[(benzo[h]quinazolin-2-yl)sulfanyl]-3,3-dimethylbutan-2-one, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dual specificity protein phosphatase 10 | Authors: | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | Deposit date: | 2022-04-07 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
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7UMV
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((5,6-dihydropyrido[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | Descriptor: | 1-{[(10aP)-5,6-dihydropyrido[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, ACETATE ION, Dual specificity protein phosphatase 10 | Authors: | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | Deposit date: | 2022-04-07 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
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4JNB
| Crystal structure of the Catalytic Domain of Human DUSP12 | Descriptor: | Dual specificity protein phosphatase 12, SULFATE ION | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-15 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMJ
| Structure of dusp11 | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-14 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMK
| Structure of dusp8 | Descriptor: | Dual specificity protein phosphatase 8, SULFATE ION | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-14 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4KI9
| Crystal structure of the catalytic domain of human DUSP12 at 2.0 A resolution | Descriptor: | Dual specificity protein phosphatase 12, PHOSPHATE ION | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-05-02 | Release date: | 2014-02-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases Acta Crystallogr.,Sect.D, 70, 2014
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7Y4E
| Crystal structure of DUSP10 mutant_N130A | Descriptor: | Dual specificity protein phosphatase 10 | Authors: | Hu, I.C, Lyu, P.C. | Deposit date: | 2022-06-14 | Release date: | 2023-06-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of DUSP10 mutant_N130A To Be Published
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7Y4D
| Crystal structure of DUSP10 mutant_S95A | Descriptor: | Dual specificity protein phosphatase 10 | Authors: | Hu, I.C, Lyu, P.C. | Deposit date: | 2022-06-14 | Release date: | 2023-06-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Crystal structure of DUSP10 mutant_S95A To Be Published
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7Y4C
| Crystal structure of DUSP10 | Descriptor: | Dual specificity protein phosphatase 10 | Authors: | Hu, I.C, Lyu, P.C. | Deposit date: | 2022-06-14 | Release date: | 2023-06-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structure of DUSP10 To Be Published
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7Y4B
| Crystal structure of DUSP10 mutant_D59A | Descriptor: | Dual specificity protein phosphatase 10 | Authors: | Hu, I.C, Lyu, P.C. | Deposit date: | 2022-06-14 | Release date: | 2023-06-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of DUSP10 mutant_D59A To Be Published
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4KYQ
| Structure of a product bound plant phosphatase | Descriptor: | CITRATE ANION, Phosphoglucan phosphatase LSF2, chloroplastic | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | Deposit date: | 2013-05-29 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation. Plant Cell, 25, 2013
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4KYR
| Structure of a product bound plant phosphatase | Descriptor: | PHOSPHATE ION, Phosphoglucan phosphatase LSF2, chloroplastic, ... | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | Deposit date: | 2013-05-29 | Release date: | 2013-07-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation. Plant Cell, 25, 2013
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4MBB
| Cubic crystal form of PIR1 dual specificity phosphatase core | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | Authors: | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | Deposit date: | 2013-08-19 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase. Biochemistry, 53, 2014
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5XJV
| Two intermediate states of conformation switch in dual specificity phosphatase 13a | Descriptor: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | Authors: | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | Deposit date: | 2017-05-04 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Two intermediate states of the conformational switch in dual specificity phosphatase 13a Pharmacol. Res., 128, 2018
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1VHR
| HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION | Authors: | Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A. | Deposit date: | 1996-02-20 | Release date: | 1996-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the dual specificity protein phosphatase VHR. Science, 272, 1996
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6L1S
| Crystal structure of DUSP22 mutant_C88S | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Chang, C.C, Lyu, P.C. | Deposit date: | 2019-09-30 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3611 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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1WRM
| Crystal structure of JSP-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, dual specificity phosphatase 22 | Authors: | Yokota, T, Kashima, A, Kato, R, Sugio, S. | Deposit date: | 2004-10-22 | Release date: | 2005-10-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution Proteins, 66, 2006
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6LMY
| Crystal structure of DUSP22 mutant_C88S/S93A | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2019-12-27 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LOT
| Crystal structure of DUSP22 mutant_N128D | Descriptor: | Dual specificity protein phosphatase 22, SULFATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-01-07 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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