3I3E
| E. COLI (lacZ) BETA-GALACTOSIDASE (M542A) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. | 登録日 | 2009-06-30 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
|
|
3I3B
| E.coli (lacz) Beta-Galactosidase (M542A) in Complex with D-Galactopyranosyl-1-on | 分子名称: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | 著者 | Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. | 登録日 | 2009-06-30 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
|
|
2X09
| Inhibition of the exo-beta-D-glucosaminidase CsxA by a glucosamine- configured castanospermine and an amino-australine analogue | 分子名称: | AMINO-AUSTRALINE, CADMIUM ION, EXO-BETA-D-GLUCOSAMINIDASE | 著者 | Pluvinage, B, Ghinet, M.G, Brzezinski, R, Boraston, A.B, Stubbs, K.A. | 登録日 | 2009-12-07 | 公開日 | 2010-02-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibition of the Exo-Beta-D-Glucosaminidase Csxa by a Glucosamine-Configured Castanospermine and an Amino-Australine Analogue. Org.Biomol.Chem., 7, 2009
|
|
3IAP
| E. coli (lacZ) beta-galactosidase (E416Q) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E. | 登録日 | 2009-07-14 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry Protein J., 29, 2010
|
|
3IAQ
| E. coli (lacz) beta-galactosidase (E416V) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E. | 登録日 | 2009-07-14 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry Protein J., 29, 2010
|
|
2X05
| Inhibition of the exo-beta-D-glucosaminidase CsxA by a glucosamine- configured castanospermine and an amino-australine analogue | 分子名称: | AMINO-CASTANOSPERMINE, CADMIUM ION, EXO-BETA-D-GLUCOSAMINIDASE | 著者 | Pluvinage, B, Ghinet, M.G, Brzezinski, R, Boraston, A.B, Stubbs, K.A. | 登録日 | 2009-12-05 | 公開日 | 2009-12-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibition of the Exo-Beta-D-Glucosaminidase Csxa by a Glucosamine-Configured Castanospermine and an Amino-Australine Analogue. Org.Biomol.Chem., 7, 2009
|
|
3HN3
| Human beta-glucuronidase at 1.7 A resolution | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Klei, H.E, Ghosh, K, Anumula, R. | 登録日 | 2009-05-29 | 公開日 | 2009-12-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human beta-glucuronidasel at 1.7 A resolution To be Published
|
|
3E1F
| |
3CZJ
| E. COLI (lacZ) BETA-GALACTOSIDASE (N460T) IN COMPLEX WITH D-GALCTOPYRANOSYL-1-ONE | 分子名称: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | 著者 | Huber, R.E, Dugdale, M.L, Fraser, M.E, Tammam, S.D. | 登録日 | 2008-04-29 | 公開日 | 2009-04-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Practical Considerations When Using Temperature to Obtain Rate Constants and Activation Thermodynamics of Enzymes with Two Catalytic Steps: Native and N460T-beta-Galactosidase (E. coli) as Examples. Protein J., 28, 2009
|
|
3GM8
| Crystal structure of a beta-glycosidase from Bacteroides vulgatus | 分子名称: | GLYCEROL, Glycoside hydrolase family 2, candidate beta-glycosidase | 著者 | Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-03-13 | 公開日 | 2009-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of a beta-glycosidase from Bacteroides vulgatus To be Published
|
|
2WBK
| Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis | 分子名称: | 1,2-ETHANEDIOL, 2,4-dinitrophenyl 2-deoxy-2-fluoro-beta-D-mannopyranoside, BETA-MANNOSIDASE, ... | 著者 | Offen, W.A, Zechel, D.L, Withers, S.G, Gilbert, H.J, Davies, G.J. | 登録日 | 2009-03-02 | 公開日 | 2009-03-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the Michaelis Complex of Beta-Mannosidase, Man2A, Provides Insight Into the Conformational Itinerary of Mannoside Hydrolysis. Cell(Cambridge,Mass.), 18, 2009
|
|
3FN9
| |
3DYO
| E. coli (lacZ) beta-galactosidase (H418N) in complex with IPTG | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | 登録日 | 2008-07-28 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli). Protein Sci., 18, 2009
|
|
3DYM
| E. coli (lacZ) beta-galactosidase (H418E) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | 登録日 | 2008-07-28 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli). Protein Sci., 18, 2009
|
|
3DYP
| E. coli (lacZ) beta-galactosidase (H418N) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | 登録日 | 2008-07-28 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli). Protein Sci., 18, 2009
|
|
2VZT
| Complex of Amycolatopsis orientalis exo-chitosanase CsxA E541A with PNP-beta-D-glucosamine | 分子名称: | 4-nitrophenyl 2-amino-2-deoxy-beta-D-glucopyranoside, ACETATE ION, CADMIUM ION, ... | 著者 | Lammerts van Bueren, A, Ghinet, M.G, Gregg, K, Fleury, A, Brzezinski, R, Boraston, A.B. | 登録日 | 2008-08-05 | 公開日 | 2008-10-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. J.Mol.Biol., 385, 2009
|
|
2VZV
| Substrate Complex of Amycolatopsis orientalis exo-chitosanase CsxA E541A with chitosan | 分子名称: | 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, EXO-BETA-D-GLUCOSAMINIDASE | 著者 | Lammerts van Bueren, A, Ghinet, M.G, Gregg, K, Fleury, A, Brzezinski, R, Boraston, A.B. | 登録日 | 2008-08-05 | 公開日 | 2008-10-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. J.Mol.Biol., 385, 2009
|
|
2VZO
| Crystal structure of Amycolatopsis orientalis exo-chitosanase CsxA | 分子名称: | ACETATE ION, CADMIUM ION, EXO-BETA-D-GLUCOSAMINIDASE, ... | 著者 | Lammerts van Bueren, A, Ghinet, M.G, Gregg, K, Fleury, A, Brzezinski, R, Boraston, A.B. | 登録日 | 2008-08-05 | 公開日 | 2008-10-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. J.Mol.Biol., 385, 2009
|
|
2VZS
| Chitosan Product complex of Amycolatopsis orientalis exo-chitosanase CsxA | 分子名称: | 2-amino-2-deoxy-beta-D-glucopyranose, CADMIUM ION, EXO-BETA-D-GLUCOSAMINIDASE, ... | 著者 | Lammerts van Bueren, A, Ghinet, M.G, Gregg, K, Fleury, A, Brzezinski, R, Boraston, A.B. | 登録日 | 2008-08-05 | 公開日 | 2008-10-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. J.Mol.Biol., 385, 2009
|
|
2VZU
| Complex of Amycolatopsis orientalis exo-chitosanase CsxA D469A with PNP-beta-D-glucosamine | 分子名称: | 4-nitrophenyl 2-amino-2-deoxy-beta-D-glucopyranoside, ACETATE ION, CADMIUM ION, ... | 著者 | Lammerts van Bueren, A, Ghinet, M.G, Gregg, K, Fleury, A, Brzezinski, R, Boraston, A.B. | 登録日 | 2008-08-05 | 公開日 | 2008-10-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. J.Mol.Biol., 385, 2009
|
|
3DEC
| Crystal structure of a glycosyl hydrolases family 2 protein from Bacteroides thetaiotaomicron | 分子名称: | Beta-galactosidase, POTASSIUM ION | 著者 | Kumaran, D, Bonanno, J, Romero, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-06-09 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of a Glycosyl Hydrolases Family 2 protein from Bacteroides thetaiotaomicron. To be Published
|
|
3CMG
| Crystal structure of putative beta-galactosidase from Bacteroides fragilis | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | 著者 | Ramagopal, U.A, Rutter, M, Toro, R, Hu, S, Maletic, M, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-03-21 | 公開日 | 2008-04-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of putative beta-galactosidase from Bacteroides fragilis. To be published
|
|
2VQT
| Structural and biochemical evidence for a boat-like transition state in beta-mannosidases | 分子名称: | (2Z,3R,4S,5R,6R)-2-[(2-aminoethyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, BETA-MANNOSIDASE, ... | 著者 | Tailford, L.E, Offen, W.A, Smith, N.L, Dumon, C, Moreland, C, Gratien, J, Heck, M.P, Stick, R.V, Bleriot, Y, Vasella, A, Gilbert, H.J, Davies, G.J. | 登録日 | 2008-03-18 | 公開日 | 2008-04-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases. Nat.Chem.Biol., 4, 2008
|
|
2VR4
| Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure | 分子名称: | (2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, BETA-MANNOSIDASE, ... | 著者 | Tailford, L.E, Offen, W.A, Smith, N.L, Dumon, C, Moreland, C, Gratien, J, Heck, M.P, Stick, R.V, Bleriot, Y, Vasella, A, Gilbert, H.J, Davies, G.J. | 登録日 | 2008-03-25 | 公開日 | 2008-04-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases. Nat.Chem.Biol., 4, 2008
|
|
2VL4
| Structural and biochemical evidence for a boat-like transition state in beta-mannosidases | 分子名称: | (2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 1,2-ETHANEDIOL, BETA-MANNOSIDASE, ... | 著者 | Tailford, L.E, Offen, W.A, Smith, N.L, Dumon, C, Moreland, C, Gratien, J, Heck, M.P, Stick, R.V, Bleriot, Y, Vasella, A, Gilbert, H.J, Davies, G.J. | 登録日 | 2008-01-08 | 公開日 | 2008-04-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases. Nat.Chem.Biol., 4, 2008
|
|