PDB: 248 resultsInfo pagesStatus searchChemie searchBIRD

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1HI8	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 Descriptor: MAGNESIUM ION, P2 PROTEIN Authors: Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. Deposit date: 2001-01-03 Release date: 2001-03-27 Last modified: 2019-09-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
7W9S	Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... Authors: Wang, M, Gong, P. Deposit date: 2021-12-10 Release date: 2022-11-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis. Nucleic Acids Res., 50, 2022
1KHV	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ Descriptor: LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE Authors: Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. Deposit date: 2001-12-01 Release date: 2002-01-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
5F8H	Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form) Descriptor: Genome polyprotein, MAGNESIUM ION, RNA (35-MER), ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
5F8G	Enterovirus 71 Polymerase Elongation Complex (C1S1 Form) Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
5F8N	Enterovirus 71 Polymerase Elongation Complex (C3S6 Form) Descriptor: GLYCEROL, Genome polyprotein, PYROPHOSPHATE 2-, ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.484 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
5F8I	Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, Genome polyprotein, ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
5F8M	Enterovirus 71 Polymerase Elongation Complex (C3S4/5 Form) Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
5I61	Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
3UQS	Crystal structures of murine norovirus RNA-dependent RNA polymerase Descriptor: RNA-dependent RNA polymerase, SULFATE ION Authors: Milani, M, Mastrangelo, E, Bolognesi, M. Deposit date: 2011-11-21 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
6KWR	Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form) Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (31-MER), ... Authors: Shi, W, Gong, P. Deposit date: 2019-09-08 Release date: 2019-12-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Res., 48, 2020
6KWQ	Crystal structure of enterovirus 71 polymerase elongation complex (native form) Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ... Authors: Shi, W, Gong, P. Deposit date: 2019-09-08 Release date: 2019-12-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Res., 48, 2020
6L4R	Crystal structure of Enterovirus D68 RdRp Descriptor: RdRp Authors: Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D. Deposit date: 2019-10-21 Release date: 2020-06-10 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.147 Å) Cite: Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 211, 2020
6LSE	Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form) Descriptor: Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ... Authors: Wang, M, Shu, B, Jing, X, Gong, P. Deposit date: 2020-01-17 Release date: 2020-04-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
6LSF	Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form) Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... Authors: Wang, M, Shu, B, Jing, X, Gong, P. Deposit date: 2020-01-17 Release date: 2020-04-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.152 Å) Cite: Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
6LSH	Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form) Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... Authors: Li, R, Wang, M, Jing, X, Gong, P. Deposit date: 2020-01-17 Release date: 2020-04-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.231 Å) Cite: Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
6LSG	Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form) Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... Authors: Li, R, Wang, M, Jing, X, Gong, P. Deposit date: 2020-01-17 Release date: 2020-04-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
4A8S	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8M	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8K	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*AP*AP*TP*CP)-3', 5'-D(*TP*CP)-3', GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8Q	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*DTP*TP*CP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8W	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8F	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*DAP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8Y	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012

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