PDB: 96 resultsInfo pagesStatus searchChemie searchBIRD

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6COZ	Human CLC-1 chloride ion channel, C-terminal cytosolic domain Descriptor: Chloride channel protein 1 Authors: Park, E, MacKinnon, R. Deposit date: 2018-03-13 Release date: 2018-06-13 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Structure of the CLC-1 chloride channel fromHomo sapiens. Elife, 7, 2018
8GA0	CLC-ec1 E202Y at pH 4.5 100mM Cl Turn Descriptor: H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
8GAH	CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Twist Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
8GA3	CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Turn Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
8GA1	CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Swap Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
8GA5	CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Intermediate Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
8GQU	AK-42 inhibitor binding human ClC-2 TMD Descriptor: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 Authors: Wang, L. Deposit date: 2022-08-30 Release date: 2023-07-05 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
4LOU	Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide Descriptor: Fab heavy chain, Fab light chain, H(+)/Cl(-) exchange transporter ClcA Authors: Lim, H.-H, Miller, C. Deposit date: 2013-07-13 Release date: 2013-08-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.981 Å) Cite: A fluoride interloper in a CLC-type Cl /H+ antiporter Nat.Chem.Biol., 2013
4KK9	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (2.997 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJW	Structure of the CLC-ec1 deltaNC construct in 100mM fluoride and 20mM bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKA	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJQ	Structure of the CLC-ec1 deltaNC construct in 100mM fluoride Descriptor: FLUORIDE ION, Fab, heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (2.875 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKL	Structure of the E148A mutant of CLC-ec1 delta NC construct in 100mM fluoride Descriptor: FLUORIDE ION, Fab, heavy chain, ... Authors: Stockbridge, R.B, Lim, H.-H, Miller, C. Deposit date: 2013-05-06 Release date: 2013-08-21 Last modified: 2013-12-04 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJP	Structure of the CLC-ec1 deltaNC construct in the absence of halide Descriptor: H(+)/Cl(-) exchange transporter ClcA, heavy chain of Fab fragment, light chain of Fab fragment Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KK6	Structure of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: BROMIDE ION, Fab, heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3.183 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKC	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-12-04 Method: X-RAY DIFFRACTION (3.18 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
3EJZ	Structure of E203V mutant E.coli Cl-/H+ exchanger, CLC-ec1 Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2008-09-18 Release date: 2009-02-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger. J.Gen.Physiol., 133, 2009
1OTS	Structure of the Escherichia coli ClC Chloride channel and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-22 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
1OTU	Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-23 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
1OTT	Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-23 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
2EXY	Crystal structure of the E148Q Mutant of EcClC, Fab complexed in absence of bound ions Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-09 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
2HT2	Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-25 Release date: 2006-09-19 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
2HLF	Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex Descriptor: BROMIDE ION, Fab Fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-07 Release date: 2006-09-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger J.Mol.Biol., 362, 2006
2HT3	Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-25 Release date: 2006-09-19 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Synergism between halide binding and proton transport in a CLC-type exchanger J.Mol.Biol., 362, 2006
2H2S	Crystal Structure of E148A mutant of CLC-ec1 in SeCN- Descriptor: CLC Cl transporter, FAB fragment, heavy chain, ... Authors: Nguitragool, W, Miller, C. Deposit date: 2006-05-19 Release date: 2006-05-30 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions J.Mol.Biol., 362, 2006

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