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8JPJ
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Cryo-EM structure of ClC-6 apo state
分子名称: CHLORIDE ION, H(+)/Cl(-) exchange transporter 6
著者Zhang, S.S.
登録日2023-06-12
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
8JPR
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Cryo-EM structure of Y553C human ClC-6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ...
著者Zhang, S.S.
登録日2023-06-12
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
8JPO
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Cryo-EM structure of ATP bound human ClC-6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ...
著者Zhang, S.S.
登録日2023-06-12
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
分子名称: 3'-(7-diethylaminocoumarin-3-carbonylamino)-3'-deoxy-ADP, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, ...
著者Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J.
登録日2011-02-17
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YVX
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Crystal structure of magnesium transporter MgtE
分子名称: MAGNESIUM ION, Mg2+ transporter MgtE
著者Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
登録日2007-04-18
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
2YVZ
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Crystal structure of magnesium transporter MgtE cytosolic domain, Mg2+-free form
分子名称: Mg2+ transporter MgtE
著者Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
登録日2007-04-18
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
2YVY
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Crystal structure of magnesium transporter MgtE cytosolic domain, Mg2+ bound form
分子名称: MAGNESIUM ION, Mg2+ transporter MgtE
著者Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
登録日2007-04-18
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
2Y8L
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Structure of the regulatory fragment of mammalian aMPK in complex with two ADP
分子名称: 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J.
登録日2011-02-07
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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Structure of the regulatory fragment of mammalian AMPK in complex with one ADP
分子名称: 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J.
登録日2011-02-09
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
5LXQ
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Structure of PRL-1 in complex with the Bateman domain of CNNM2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1, ...
著者GIMENEZ-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-ORBEA, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M, Martinez-Cruz, L.A.
登録日2016-09-22
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.335 Å)
主引用文献Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
5MMZ
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Structure of PRL-1 in complex with the Bateman domain of CNNM2
分子名称: Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1
著者Gimenez-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-Orbea, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M.L, Martinez-Cruz, L.A.
登録日2016-12-12
公開日2016-12-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
2ZY9
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Improved crystal structure of magnesium transporter MgtE
分子名称: MAGNESIUM ION, Mg2+ transporter MgtE
著者Nureki, O, Ishitani, R, Hattori, M.
登録日2009-01-19
公開日2009-12-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis
Embo J., 28, 2009
3T4N
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BU of 3t4n by Molmil
Structure of the regulatory fragment of Saccharomyces cerevisiae AMPK in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ...
著者Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmdit, M.C, Gamblin, S.J, Carling, D.
登録日2011-07-26
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TE5
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structure of the regulatory fragment of sacchromyces cerevisiae ampk in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ...
著者Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D.
登録日2011-08-12
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TDH
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BU of 3tdh by Molmil
Structure of the regulatory fragment of sccharomyces cerevisiae AMPK in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ...
著者Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D.
登録日2011-08-11
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3L2B
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BU of 3l2b by Molmil
Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with activator, diadenosine tetraphosphate
分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase
著者Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R.
登録日2009-12-15
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
7BXU
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BU of 7bxu by Molmil
CLC-7/Ostm1 membrane protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1
著者Zhang, S.S, Yang, M.J.
登録日2020-04-20
公開日2020-09-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular insights into the human CLC-7/Ostm1 transporter.
Sci Adv, 6, 2020
3KXR
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BU of 3kxr by Molmil
Structure of the cystathionine beta-synthase pair domain of the putative Mg2+ transporter SO5017 from Shewanella oneidensis MR-1.
分子名称: CHLORIDE ION, Magnesium transporter, putative
著者Fratczak, Z, Zimmerman, M.D, Chruszcz, M, Cymborowski, M, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2009-12-03
公開日2009-12-15
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structure of the cystathionine beta-synthase pair domain of the putative Mg2+ transporter SO5017 from Shewanella oneidensis MR-1.
To be Published
3L31
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BU of 3l31 by Molmil
Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with the inhibitor, AMP
分子名称: ADENOSINE MONOPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase
著者Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R.
登録日2009-12-16
公開日2010-04-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
7CQ5
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BU of 7cq5 by Molmil
Structure of the human CLCN7-OSTM1 complex with ATP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
登録日2020-08-08
公開日2020-11-11
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure of the human CLCN7-OSTM1 complex with ATP
To Be Published
7CQ7
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Structure of the human CLCN7-OSTM1 complex with ADP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
登録日2020-08-08
公開日2020-11-11
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structure of the human CLCN7-OSTM1 complex with ADP
To Be Published
7CQ6
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Structure of the human CLCN7-OSTM1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, H(+)/Cl(-) exchange transporter 7, ...
著者Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
登録日2020-08-08
公開日2020-11-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the human CLCN7-OSTM1 complex
To Be Published
4EAI
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BU of 4eai by Molmil
Co-crystal structure of an AMPK core with AMP
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W.
登録日2012-03-22
公開日2012-06-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAK
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BU of 4eak by Molmil
Co-crystal structure of an AMPK core with ATP
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W.
登録日2012-03-22
公開日2012-06-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAJ
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BU of 4eaj by Molmil
Co-crystal of AMPK core with AMP soaked with ATP
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W.
登録日2012-03-22
公開日2012-06-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012

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