6D0S
 
 | | RabGAP domain of human TBC1D22B | | 分子名称: | SULFATE ION, TBC1 domain family member 22B, UNKNOWN ATOM OR ION | | 著者 | Tong, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-04-10 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | RabGAP domain of human TBC1D22B
To be Published
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3HZJ
 | | Crystal structure of the RabGAP domain of the RABGAP1L protein | | 分子名称: | RAB GTPase-activating protein 1-like, UNKNOWN ATOM OR ION | | 著者 | Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-06-23 | | 公開日 | 2009-07-14 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the RabGAP domain of the RABGAP1L protein
To be Published
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4Z6Y
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1FKM
 | | CRYSTAL STRUCTURE OF THE YPT/RAB-GAP DOMAIN OF GYP1P | | 分子名称: | PROTEIN (GYP1P) | | 著者 | Rak, A, Fedorov, R, Alexandrov, K, Albert, S, Goody, R.S, Gallwitz, D, Scheidig, A.J. | | 登録日 | 2000-08-09 | | 公開日 | 2001-02-09 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins.
EMBO J., 19, 2000
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4NC6
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5EJC
 | | Crystal structural of the TSC1-TBC1D7 complex | | 分子名称: | Hamartin, TBC1 domain family member 7 | | 著者 | Wang, Z, Qin, J, Gong, W, Xu, W. | | 登録日 | 2015-11-01 | | 公開日 | 2016-03-02 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
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5HJN
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5HJQ
 | | Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster in complex with inositol(1,4,5)triphosphate | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, LD10117p | | 著者 | Fischer, B, Paesmans, J, Versees, W. | | 登録日 | 2016-01-13 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Nat.Struct.Mol.Biol., 23, 2016
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5TUB
 | | Crystal Structure of the Shark TBC1D15 GAP Domain | | 分子名称: | Shark TBC1D15 GTPase-activating Protein | | 著者 | Chen, Y.-N, Wang, W, Cheng, D, Ge, Y, Gu, X, Zhou, X.E, Ye, F, Xu, H.E, Lv, Z. | | 登録日 | 2016-11-05 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
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5TUC
 | | Crystal Structure of the Sus TBC1D15 GAP Domain | | 分子名称: | Sus TBC1D15 GAP Domain | | 著者 | Chen, Y.-N, Wang, W, Cheng, D, Ge, Y, Gu, X, Zhou, X.E, Ye, F, Xu, H.E, Lv, Z. | | 登録日 | 2016-11-05 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
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4HL4
 | | Crystal structure of the human TBC1D20 RabGAP domain | | 分子名称: | ACETATE ION, BERYLLIUM TRIFLUORIDE ION, TBC1 domain family member 20 | | 著者 | Gazdag, E.M, Gavriljuk, K, Itzen, A, Koetting, C, Gerwert, K, Goody, R.S. | | 登録日 | 2012-10-16 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2QFZ
 | | Crystal structure of human TBC1 domain family member 22A | | 分子名称: | TBC1 domain family member 22A, UNKNOWN ATOM OR ION | | 著者 | Tong, Y, Tempel, W, Dimov, S, Dong, A, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2007-06-28 | | 公開日 | 2007-07-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human TBC1 domain family member 22A.
To be Published
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2QQ8
 | | Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14 | | 分子名称: | TBC1 domain family member 14, UNKNOWN ATOM OR ION | | 著者 | Tong, Y, Tempel, W, Dimov, S, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2007-07-26 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14.
To be Published
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3QWL
 | | Crystal structure of human TBC1 domain family member 7 | | 分子名称: | TBC1 domain family member 7, UNKNOWN ATOM OR ION | | 著者 | Guan, X, Tempel, W, Tong, Y, Wernimont, A.K, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-02-28 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human TBC1 domain family member 7
to be published
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3QYB
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3QYE
 | | Crystal Structure of Human TBC1D1 RabGAP domain | | 分子名称: | TBC1 domain family member 1 | | 著者 | Park, S.Y, Shoelson, S.E. | | 登録日 | 2011-03-03 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
J.Biol.Chem., 286, 2011
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6JL7
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7DL2
 | | Cryo-EM structure of human TSC complex | | 分子名称: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | | 著者 | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | | 登録日 | 2020-11-25 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural insights into TSC complex assembly and GAP activity on Rheb.
Nat Commun, 12, 2021
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2G77
 | | Crystal Structure of Gyp1 TBC domain in complex with Rab33 GTPase bound to GDP and AlF3 | | 分子名称: | ALUMINUM FLUORIDE, GTPase-activating protein GYP1, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Pan, X, Eathiraj, S, Munson, M, Lambright, D.G. | | 登録日 | 2006-02-27 | | 公開日 | 2006-07-25 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Nature, 442, 2006
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4HLQ
 | | Crystal structure of human rab1b bound to GDP and BEF3 in complex with the GAP domain of TBC1D20 from homo sapiens | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Gazdag, E.M, Gavriljuk, K, Itzen, A, Koetting, C, Gerwert, K, Goody, R.S. | | 登録日 | 2012-10-17 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail.
Proc.Natl.Acad.Sci.USA, 109, 2012
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