PDB: 675 件ウェブページステータス検索Chemie searchBIRD

---

2WUF	Crystal structure of S114A mutant of HsaD from Mycobacterium tuberculosis in complex with 4,9DSHA 分子名称: (3E,5R)-8-[(1S,3AR,4R,7AS)-1-HYDROXY-7A-METHYL-5-OXOOCTAHYDRO-1H-INDEN-4-YL]-5-METHYL-2,6-DIOXOOCT-3-ENOATE, 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD, GLYCEROL, ... 著者 Lack, N.A, Yam, K.C, Lowe, E.D, Horsman, G.P, Owen, R, Sim, E, Eltis, L.D. 登録日 2009-10-02 公開日 2009-10-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism. J. Biol. Chem., 285, 2010
1A88	CHLOROPEROXIDASE L 分子名称: CHLOROPEROXIDASE L 著者 Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J. 登録日 1998-04-03 公開日 1998-10-14 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural investigation of the cofactor-free chloroperoxidases. J.Mol.Biol., 279, 1998
2XUA	Crystal structure of the enol-lactonase from Burkholderia xenovorans LB400 分子名称: 3-OXOADIPATE ENOL-LACTONASE, LAEVULINIC ACID 著者 Bains, J, Kaufman, L, Farnell, B, Boulanger, M.J. 登録日 2010-10-17 公開日 2011-01-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Product Analog Bound Form of 3-Oxoadipate-Enol- Lactonase (Pcad) Reveals a Multifunctional Role for the Divergent CAP Domain. J.Mol.Biol., 406, 2011
1EDE	REFINED X-RAY STRUCTURES OF HALOALKANE DEHALOGENASE AT PH 6.2 AND PH 8.2 AND IMPLICATIONS FOR THE REACTION MECHANISM 分子名称: HALOALKANE DEHALOGENASE 著者 Verschueren, K.H.G, Dijkstra, B.W. 登録日 1993-05-13 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism. J.Mol.Biol., 232, 1993
6PUX	Homoserine transacetylase MetX from Mycobacterium tuberculosis 分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ... 著者 Chaton, C.T, Korotkov, K.V. 登録日 2019-07-18 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site. Sci Rep, 9, 2019
2XT0	Dehalogenase DPpA from Plesiocystis pacifica SIR-I 分子名称: HALOALKANE DEHALOGENASE, SULFATE ION 著者 Bogdanovic, X, Palm, G.J, Hinrichs, W. 登録日 2010-10-02 公開日 2011-08-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cloning, Functional Expression, Biochemical Characterization, and Structural Analysis of a Haloalkane Dehalogenase from Plesiocystis Pacifica Sir-1. Appl.Microbiol.Biotechnol., 91, 2011
5AKK	ligand complex structure of soluble epoxide hydrolase 分子名称: 6-bromo-1,3-dihydro-2H-indol-2-one, BIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-03 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
6QI1	Time resolved structural analysis of the full turnover of an enzyme - 12312 ms 分子名称: Fluoroacetate dehalogenase, fluoroacetic acid 著者 Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. 登録日 2019-01-17 公開日 2019-09-25 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
5ALH	ligand complex structure of soluble epoxide hydrolase 分子名称: 4-[[(2-methoxy-5-methyl-phenyl)sulfonylamino]methyl]-4-phenyl-N-(p-tolylmethyl)piperidine-1-carboxamide, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5H3H	Esterase (EaEST) from Exiguobacterium antarcticum 分子名称: Abhydrolase domain-containing protein, ETHANEPEROXOIC ACID 著者 Lee, J.H, Lee, C.W. 登録日 2016-10-24 公開日 2017-01-11 最終更新日 2022-10-19 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum. Plos One, 12, 2017
6N00	Fluoroacetate dehalogenase, room temperature structure, using last 1 degree of total 3 degree oscillation and 144 kGy dose 分子名称: CALCIUM ION, Fluoroacetate dehalogenase 著者 Finke, A.D, Wierman, J.L, Pare-Labrosse, O, Sarrachini, A, Besaw, J, Mehrabi, P, Gruner, S.M, Miller, R.J.D. 登録日 2018-11-06 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fixed-target serial oscillation crystallography at room temperature. IUCrJ, 6, 2019
5ALY	ligand complex structure of soluble epoxide hydrolase 分子名称: 5-(7-fluoranyl-3,3-dimethyl-2-oxidanylidene-1H-indol-5-yl)-4-methyl-1H-pyrazole-3-carbonitrile, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
6YN2	Crystal structure of Renilla reniformis luciferase variant RLuc8-W121F/E144Q in complex with a coelenteramide (the postcatalytic enzyme-product complex) 分子名称: ACETATE ION, Coelenterazine h 2-monooxygenase, GLYCEROL, ... 著者 Damborsky, J, Marek, M. 登録日 2020-04-10 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Engineering the protein dynamics of an ancestral luciferase. Nat Commun, 12, 2021
1YAS	HYDROXYNITRILE LYASE COMPLEXED WITH HISTIDINE 分子名称: HISTIDINE, HYDROXYNITRILE LYASE, SULFATE ION 著者 Wagner, U.G, Kratky, C. 登録日 1996-05-15 公開日 1997-06-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism of cyanogenesis: the crystal structure of hydroxynitrile lyase from Hevea brasiliensis. Structure, 4, 1996
3WWP	S-selective hydroxynitrile lyase from Baliospermum montanum (apo2) 分子名称: (S)-hydroxynitrile lyase, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Nakano, S, Dadashipour, M, Asano, Y. 登録日 2014-06-23 公開日 2014-10-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics Biochim.Biophys.Acta, 1844, 2014
3HEA	The L29P/L124I mutation of Pseudomonas fluorescens esterase 分子名称: Arylesterase, ETHYL ACETATE, GLYCEROL, ... 著者 Kazlauskas, R.J, Schrag, J.D, Cheeseman, J.D, Morley, K.L. 登録日 2009-05-08 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase. Biochemistry, 49, 2010
2HAD	CRYSTAL STRUCTURE OF HALOALKANE DEHALOGENASE: AN ENZYME TO DETOXIFY HALOGENATED ALKANES 分子名称: HALOALKANE DEHALOGENASE 著者 Verschueren, K.H.G, Franken, S.M, Dijkstra, B.W. 登録日 1992-08-07 公開日 1993-01-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes. EMBO J., 10, 1991
3HSS	A higher resolution structure of Rv0554 from Mycobacterium tuberculosis complexed with malonic acid 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Johnston, J.M, Baker, E.N. 登録日 2009-06-10 公開日 2010-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallogr.,Sect.D, 66, 2010
3NWO	Crystal structure of Proline iminopeptidase Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-07-09 公開日 2010-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2OCI	Crystal structure of valacyclovir hydrolase complexed with a product analogue 分子名称: L-TYROSINAMIDE, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Lai, L, Xu, Z, Amidon, G.L. 登録日 2006-12-20 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
2OCL	Crystal structure of valacyclovir hydrolase S122A mutant 分子名称: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase 著者 Lai, L, Xu, Z, Amidon, G.L. 登録日 2006-12-20 公開日 2008-02-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
5YB5	The complex crystal structure of VrEH2 mutant M263N with SNO 分子名称: (S)-PARA-NITROSTYRENE OXIDE, Epoxide hydrolase 著者 Li, F.L, Chen, F.F, Chen, Q, Kong, X.D, Yu, H.L, Xu, J.H. 登録日 2017-09-03 公開日 2018-09-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation Acs Catalysis, 8, 2018
3V1M	Crystal Structure of the S112A/H265Q mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400, after exposure to its substrate HOPDA 分子名称: (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, MALONATE ION 著者 Ghosh, S, Bolin, J.T. 登録日 2011-12-09 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad. J.Am.Chem.Soc., 134, 2012
5UXZ	X-ray crystal structure of Halotag bound to the P9 benzothiadiazole fluorogenic ligand 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Haloalkane dehalogenase, ... 著者 Dunham, N.P, Boal, A.K. 登録日 2017-02-23 公開日 2017-03-08 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification. Biochemistry, 56, 2017
6COC	AtHNL enantioselectivity mutant At-A9-H7 Apo, Y13C,Y121L,P126F,L128W,C131T,F179L,A209I with benzaldehyde 分子名称: Alpha-hydroxynitrile lyase, CHLORIDE ION, GLYCEROL, ... 著者 Jones, B.J, Kazlauskas, R.J, Desrouleaux, R. 登録日 2018-03-12 公開日 2019-03-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 AtHNL enantioselectivity mutants To be published

<6789101112131415161718192021>