3V1M

Crystal Structure of the S112A/H265Q mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400, after exposure to its substrate HOPDA

Summary for 3V1M

Entry DOI	10.2210/pdb3v1m/pdb
Related	2OG1 2PU7 2PUH 2PUJ 2RHT 2RHW 2RI6 3V1K 3V1L 3V1N
Descriptor	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, MALONATE ION, (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE, ... (4 entities in total)
Functional Keywords	c-c bond hydrolase, alpha/beta hydrolase fold, bphd, alpha/beta hydrolase, pcb degradation, meta cleavage product hydrolase, mcp hydrolase, 2-hydroxy-6-oxo-6-phenyl-hexa-2, 4-dienoate hydrolase, hydrolase
Biological source	Burkholderia xenovorans
Total number of polymer chains	1
Total formula weight	32361.88
Authors	Ghosh, S.,Bolin, J.T. (deposition date: 2011-12-09, release date: 2012-03-21, Last modification date: 2024-02-28)
Primary citation	Ruzzini, A.C.,Ghosh, S.,Horsman, G.P.,Foster, L.J.,Bolin, J.T.,Eltis, L.D. Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad. J.Am.Chem.Soc., 134:4615-4624, 2012 Cited by PubMed: 22339283 DOI: 10.1021/ja208544g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation