1AF3
| RAT BCL-XL AN APOPTOSIS INHIBITORY PROTEIN | 分子名称: | APOPTOSIS REGULATOR BCL-X | 著者 | Aritomi, M, Kunishima, N, Inohara, N, Ishibashi, Y, Ohta, S, Morikawa, K. | 登録日 | 1997-03-21 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family. J.Biol.Chem., 272, 1997
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1BXL
| STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BAK PEPTIDE, BCL-XL | 著者 | Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W. | 登録日 | 1996-10-16 | 公開日 | 1997-10-29 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. Science, 275, 1997
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1F16
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1G5J
| COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD | 分子名称: | APOPTOSIS REGULATOR BCL-X, BAD PROTEIN | 著者 | Petros, A.M, Nettesheim, D.G, Wang, Y, Olejniczak, E.T, Meadows, R.P, Mack, J, Swift, K, Matayoshi, E.D, Zhang, H, Thompson, C.B, Fesik, S.W. | 登録日 | 2000-11-01 | 公開日 | 2001-02-07 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies. Protein Sci., 9, 2000
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1G5M
| HUMAN BCL-2, ISOFORM 1 | 分子名称: | PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) | 著者 | Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. | 登録日 | 2000-11-01 | 公開日 | 2001-03-21 | 最終更新日 | 2022-12-21 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001
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1GJH
| HUMAN BCL-2, ISOFORM 2 | 分子名称: | PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) | 著者 | Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. | 登録日 | 2001-05-31 | 公開日 | 2001-06-13 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001
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1K3K
| Solution Structure of a Bcl-2 Homolog from Kaposi's Sarcoma Virus | 分子名称: | functional anti-apoptotic factor vBCL-2 homolog | 著者 | Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T. | 登録日 | 2001-10-03 | 公開日 | 2002-04-10 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus. Proc.Natl.Acad.Sci.USA, 99, 2002
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1LXL
| NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BCL-XL | 著者 | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | 登録日 | 1996-04-04 | 公開日 | 1997-04-21 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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1MAZ
| X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH | 分子名称: | Bcl-2-like protein 1 | 著者 | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | 登録日 | 1996-04-09 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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1MK3
| SOLUTION STRUCTURE OF HUMAN BCL-W PROTEIN | 分子名称: | Apoptosis regulator Bcl-W | 著者 | Denisov, A.Y, Madiraju, M.S, Chen, G, Khadir, A, Beauparlant, P, Attardo, G, Shore, G.C, Gehring, K. | 登録日 | 2002-08-28 | 公開日 | 2003-06-03 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix J.BIOL.CHEM., 278, 2003
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1O0L
| THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY | 分子名称: | Apoptosis regulator Bcl-W | 著者 | Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L. | 登録日 | 2003-02-22 | 公開日 | 2003-04-01 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity Embo J., 22, 2003
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1OHU
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1PQ0
| Crystal structure of mouse Bcl-xl | 分子名称: | Apoptosis regulator Bcl-X | 著者 | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | 登録日 | 2003-06-17 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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1PQ1
| Crystal structure of Bcl-xl/Bim | 分子名称: | Apoptosis regulator Bcl-X, BCL2-like protein 11 | 著者 | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | 登録日 | 2003-06-17 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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1Q59
| Solution Structure of the BHRF1 Protein From Epstein-Barr Virus, a Homolog of Human Bcl-2 | 分子名称: | Early antigen protein R | 著者 | Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T. | 登録日 | 2003-08-06 | 公開日 | 2003-09-23 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the BHRF1 Protein From Epstein-Barr Virus, a Homolog of Human Bcl-2 J.Mol.Biol., 332, 2003
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1R2D
| Structure of Human Bcl-XL at 1.95 Angstroms | 分子名称: | Apoptosis regulator Bcl-X | 著者 | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | 登録日 | 2003-09-26 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2E
| Human Bcl-XL containing a Glu to Leu mutation at position 92 | 分子名称: | Apoptosis regulator Bcl-X | 著者 | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | 登録日 | 2003-09-26 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2G
| Human Bcl-XL containing a Phe to Trp mutation at position 97 | 分子名称: | Apoptosis regulator Bcl-X | 著者 | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | 登録日 | 2003-09-26 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2H
| Human Bcl-XL containing an Ala to Leu mutation at position 142 | 分子名称: | Apoptosis regulator Bcl-X | 著者 | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | 登録日 | 2003-09-26 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1R2I
| Human Bcl-XL containing a Phe to Leu mutation at position 146 | 分子名称: | Apoptosis regulator Bcl-X | 著者 | O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. | 登録日 | 2003-09-26 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
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1TY4
| Crystal structure of a CED-9/EGL-1 complex | 分子名称: | Apoptosis regulator ced-9, EGg Laying defective EGL-1, programmed cell death activator | 著者 | Yan, N, Gu, L, Kokel, D, Xue, D, Shi, Y. | 登録日 | 2004-07-07 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4 Mol.Cell, 15, 2004
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1WSX
| Solution structure of MCL-1 | 分子名称: | myeloid cell leukemia sequence 1 | 著者 | Day, C.L, Chen, L, Richardson, S.J, Harrison, P.J, Huang, D.C, Hinds, M.G. | 登録日 | 2004-11-12 | 公開日 | 2004-11-23 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands J.Biol.Chem., 280, 2005
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1YSG
| Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands | 分子名称: | 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL, Apoptosis regulator Bcl-X | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | 登録日 | 2005-02-08 | 公開日 | 2005-06-07 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
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1YSI
| Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand | 分子名称: | Apoptosis regulator Bcl-X, N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | 登録日 | 2005-02-08 | 公開日 | 2005-06-07 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
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1YSN
| Solution structure of the anti-apoptotic protein Bcl-xL complexed with an acyl-sulfonamide-based ligand | 分子名称: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | 登録日 | 2005-02-08 | 公開日 | 2005-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
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