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7R42
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BU of 7r42 by Molmil
Bovine complex I in the presence of IM1761092, active class ii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R41
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BU of 7r41 by Molmil
Bovine complex I in the presence of IM1761092, active class i (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7QV7
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BU of 7qv7 by Molmil
Cryo-EM structure of Hydrogen-dependent CO2 reductase.
Descriptor: Hydrogen dependent carbon dioxide reductase subunit FdhF, Hydrogen dependent carbon dioxide reductase subunit HycB3, Hydrogen dependent carbon dioxide reductase subunit HycB4, ...
Authors:Dietrich, H.M, Righetto, R.D, Kumar, A, Wietrzynski, W, Schuller, S.K, Trischler, R, Wagner, J, Schwarz, F.M, Engel, B.D, Mueller, V, Schuller, J.M.
Deposit date:2022-01-19
Release date:2022-07-06
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Membrane-anchored HDCR nanowires drive hydrogen-powered CO 2 fixation.
Nature, 607, 2022
7QSO
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BU of 7qso by Molmil
Bovine complex I in lipid nanodisc, State 3 (Slack)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSN
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BU of 7qsn by Molmil
Bovine complex I in lipid nanodisc, Deactive-apo
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSM
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BU of 7qsm by Molmil
Bovine complex I in lipid nanodisc, Deactive-ligand (composite)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSL
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BU of 7qsl by Molmil
Bovine complex I in lipid nanodisc, Active-apo
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSK
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BU of 7qsk by Molmil
Bovine complex I in lipid nanodisc, Active-Q10
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSD
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BU of 7qsd by Molmil
Bovine complex I in the active state at 3.1 A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-01-13
Release date:2022-03-02
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7PSA
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BU of 7psa by Molmil
The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms
Descriptor: (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Grba, D, Hirst, J.
Deposit date:2021-09-22
Release date:2022-04-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J.Biol.Chem., 298, 2022
7P7M
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BU of 7p7m by Molmil
Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P7L
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BU of 7p7l by Molmil
Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P7K
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BU of 7p7k by Molmil
Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P7J
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BU of 7p7j by Molmil
Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P7E
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BU of 7p7e by Molmil
Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P7C
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BU of 7p7c by Molmil
Complex I from E. coli, DDM/LMNG-purified, Apo, Open state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-19
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P69
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BU of 7p69 by Molmil
Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-15
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P64
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BU of 7p64 by Molmil
Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-15
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P63
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BU of 7p63 by Molmil
Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Closed state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-15
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P62
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BU of 7p62 by Molmil
Complex I from E. coli, DDM-purified, Apo, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-15
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7P61
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BU of 7p61 by Molmil
Complex I from E. coli, DDM-purified, with NADH, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2021-07-15
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7O71
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BU of 7o71 by Molmil
Cryo-EM structure of a respiratory complex I
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ...
Authors:Parey, K, Vonck, J.
Deposit date:2021-04-12
Release date:2021-11-10
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
7O6Y
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BU of 7o6y by Molmil
Cryo-EM structure of respiratory complex I under turnover
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Parey, K, Vonck, J.
Deposit date:2021-04-12
Release date:2021-11-10
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
7NZ1
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BU of 7nz1 by Molmil
Respiratory complex I from Escherichia coli - focused refinement of cytoplasmic arm
Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Kolata, P, Efremov, R.G.
Deposit date:2021-03-23
Release date:2021-08-18
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation.
Elife, 10, 2021
7NYV
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BU of 7nyv by Molmil
Respiratory complex I from Escherichia coli - conformation 3
Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Kolata, P, Efremov, R.G.
Deposit date:2021-03-23
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation.
Elife, 10, 2021

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數據於2024-04-24公開中

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