7AWT
 
 | | E. coli NADH quinone oxidoreductase hydrophilic arm | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | 著者 | Schimpf, J, Grishkovskaya, I, Haselbach, D, Friedrich, T. | | 登録日 | 2020-11-09 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Structure of the peripheral arm of a minimalistic respiratory complex I.
Structure, 30, 2022
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7AQR
 | | Cryo-EM structure of Arabidopsis thaliana Complex-I (peripheral arm) | | 分子名称: | Acyl carrier protein 2, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Klusch, N, Kuehlbrandt, W, Yildiz, O. | | 登録日 | 2020-10-22 | | 公開日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7AR8
 | | Cryo-EM structure of Arabidopsis thaliana complex-I (closed conformation) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W, Yildiz, O. | | 登録日 | 2020-10-23 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7ARB
 | | Cryo-EM structure of Arabidopsis thaliana Complex-I (complete composition) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W, Yildiz, O. | | 登録日 | 2020-10-23 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7AR7
 | | Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W. | | 登録日 | 2020-10-23 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7B93
 | | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ... | | 著者 | Chung, I, Hirst, J. | | 登録日 | 2020-12-14 | | 公開日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.
Sci Adv, 7, 2021
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7NZ1
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7NYR
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7NYV
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7NYU
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7O71
 | | Cryo-EM structure of a respiratory complex I | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | | 著者 | Parey, K, Vonck, J. | | 登録日 | 2021-04-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
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7O6Y
 | | Cryo-EM structure of respiratory complex I under turnover | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | 著者 | Parey, K, Vonck, J. | | 登録日 | 2021-04-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
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7P7C
 | | Complex I from E. coli, DDM/LMNG-purified, Apo, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P62
 | | Complex I from E. coli, DDM-purified, Apo, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P69
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P61
 | | Complex I from E. coli, DDM-purified, with NADH, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7M
 | | Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7L
 | | Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7E
 | | Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P63
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Closed state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P64
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7K
 | | Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7J
 | | Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7PSA
 | | The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | | 分子名称: | (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | 著者 | Grba, D, Hirst, J. | | 登録日 | 2021-09-22 | | 公開日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J.Biol.Chem., 298, 2022
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7QSD
 | | Bovine complex I in the active state at 3.1 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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